Deep Vein Thrombosis Provoked by Inferior Vena Cava Agenesis

Haddad, Raad A.; Saadaldin, Mazin; Kumar, Binay; Bachuwa, Ghassan

doi:10.1155/2015/651436

Cited by 5 publications

(3 citation statements)

References 18 publications

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“…Five instances of IVCA were detected during electrophysiological procedures [ 7 ]. Some tests that are useful for finding and diagnosing IVCA are ultrasound, CT scan, MRI, or venogram of the abdomen [ 10 ].…”

Section: Discussionmentioning

confidence: 99%

Inferior Vena Cava Agenesis: An Underrated Cause of Deep Venous Thrombosis

Kannappan¹,

Velavan²

2023

Cureus

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The absence of the inferior vena cava (IVC) is a rare abnormality reported in less than 1% of the population. The condition is usually the result of defects during embryogenesis. The collateral veins are enlarged with agenesis IVC, enabling blood transport to the superior vena cava. Although the alternate pathways enable venous drainage of the lower extremities, IVC agenesis (IVCA) may predispose to venous hypertension and complications, including thromboembolism. This report includes a case of a 35-year-old obese male who presented with deep vein thrombosis (DVT) in his left lower extremity (LLE) with no predisposing factors, which led to an incidental discovery of the inferior vena cava agenesis. Imaging showed thrombosis of the deep veins of the LLE, absence of the IVC, enlarged paralumbar veins, filling of the superior vena cava, and left renal atrophy.The patient responded to therapeutic heparin infusion, and catheter placement and thrombectomy were performed. The patient was discharged on the third day with medications and vascular follow-up. It is essential to recognize the complications of IVCA and its correlation with other findings, such as atrophy of the kidney. The agenesis of IVC is a highly under-recognized cause of DVT of the lower extremities in the young population without other risk factors. Hence, a complete diagnostic evaluation is necessary for this age group, including imaging for vascular anomalies, besides the thrombophilic screening.

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Section: Discussionmentioning

confidence: 99%

Inferior Vena Cava Agenesis: An Underrated Cause of Deep Venous Thrombosis

Kannappan¹,

Velavan²

2023

Cureus

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“…Literature review of similar cases disclosed successful use of thrombolysis coupled with anticoagulation. [9,[11][12][13][14] Further studies are warranted to reinforce the role of thrombus removal and its long-term benefit in the treatment of iliofemoral DVT.…”

Section: Discussionmentioning

confidence: 99%

Congenital agenesis of inferior vena cava as a rare cause of deep vein thrombosis: Case report and review of the literature

Ackula

Mosalpuria

Tandra

2016

CRIM

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Inferior vena cava agenesis (IVCA) is an uncommon cause of deep vein thrombosis (DVT). We report the case of a 26-year-old Caucasian female with unilateral iliofemoral DVT. On further evaluation, CT abdomen revealed diminutive inferior vena cava consistent with IVCA. We have used systemic anticoagulation and catheter mediated thrombolysis with success in this case. Physicians should suspect IVCA in patients with extensive DVT especially in younger individuals.

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“…[ 2 ] There are many therapeutic protocols for the treatment of IVC agenesis patients complicated with DVT such as continuous heparin therapy, but many challenging issues remain. [ 3 ]…”

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confidence: 99%