Deep sedation in pediatric imaging: efficacy and safety of intravenous chlorpromazine

Vong, C. Heng; Bajard, Agathe; Thiesse, Philippe; Bouffet, Éric; Seban, H.; Bérard, P

doi:10.1007/s00247-011-2310-1

Cited by 14 publications

(7 citation statements)

References 45 publications

(48 reference statements)

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“…Observational studies report a high rate of success in imaging of moderately sedated patients (Category B3-B evidence). [123][124][125][126][127] One RCT reports equivocal findings for scan Practice Advisory Practice Advisory repeats when light anesthesia is compared with general anesthesia (Category A3-E evidence). [119][120][121][122] Observational studies report a high rate of successful imaging in patients receiving deep sedation or light anesthesia, with low rates of motion artifacts (Category B3-B evidence).…”

Section: Advisory Statements For Monitoringmentioning

confidence: 99%

Practice Advisory on Anesthetic Care for Magnetic Resonance Imaging

2015

Anesthesiology

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Section: Advisory Statements For Monitoringmentioning

confidence: 99%

Practice Advisory on Anesthetic Care for Magnetic Resonance Imaging

2015

Anesthesiology

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“…29 In small children, the predictable safety of GA may be preferred over deep sedation; sedation also has a lower success rate. 27,30 Sedation and GA carry risks of complications that necessitate continuous monitoring. 25 Adverse events (AEs) of sedation, including respiratory depression and hypoxemia, may occur in up to 20% of children.…”

mentioning

confidence: 99%

Contrast-enhanced Magnetic Resonance Imaging in Pediatric Patients: Review and Recommendations for Current Practice

Bhargava

Hahn

Hirsch³

et al. 2013

Magn Reson�Insights

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Magnetic resonance imaging (MRI), frequently with contrast enhancement, is the preferred imaging modality for many indications in children. Practice varies widely between centers, reflecting the rapid pace of change and the need for further research. Guide-line changes, for example on contrast-medium choice, require continued practice reappraisal. This article reviews recent developments in pediatric contrast-enhanced MRI and offers recommendations on current best practice. Nine leading pediatric radiologists from internationally recognized radiology centers convened at a consensus meeting in Bordeaux, France, to discuss applications of contrast-enhanced MRI across a range of indications in children. Review of the literature indicated that few published data provide guidance on best practice in pediatric MRI. Discussion among the experts concluded that MRI is preferred over ionizing-radiation modalities for many indications, with advantages in safety and efficacy. Awareness of age-specific adaptations in MRI technique can optimize image quality. Gadolinium-based contrast media are recommended for enhancing imaging quality. The choice of most appropriate contrast medium should be based on criteria of safety, tolerability, and efficacy, characterized in age-specific clinical trials and personal experience.

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“…Stability is essential in MRI because it is susceptible to motion artifacts. Repetition of the full sequence is required if any motion occurs during the imaging process for one sequence [2]. In recent years, the number of pediatric patients with MRI increased by increasing popularity; but there is a limited number of study concerning the anesthetic management of these patients.…”

Section: Introductionmentioning

confidence: 99%

Sedation in pediatric magnetic resonance imaging: a ten-year experience

Yüce¹

2018

Ann Clin Anal Med

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Aim: We aimed to evaluate anesthesia practice for pediatric magnetic resonance imaging (MRI) according to the age groups and discuss the anesthetic management of the patients. We investigated the hospital sheets of all children who underwent MRI under anesthesia retrospectively. Material and Method: We divided the total of 5720 patients included in the study into two groups as Group S: school children (>6 years) and Group PS: preschool children (<6 years). We compared the two groups according to demographic characteristics, the anesthetic agent, additional anesthetic agent requirement, length of the sedation and the complications before and after the sedation. Results: Overall, the mean age of the patients was 4.6±3.8 years (6 months-14 years). In all procedural sedation, we used the ketamine-propofol combination. In Group S, mean ketamine and propofol doses were significantly higher than Group PS (p<0.05). There was no statistically significant difference in additional anesthetic agent requirement as Ketamine and Midazolam (p=0.38, p=0.42). The duration of anesthesia was significantly longer in preschool children(p<0.05). There were no severe complications in both groups. In 148 patients we observed hypoxia (2.58%) and pain in the injection area in 114(1.99%) patients with complications due to sedation. Discussion: In pediatric MRI patients, ketamine and midazolam are effective and safe choices for procedural sedation. For safety of the sedation, it must be done in a well-equipped environment and proper dose adjustment is required.

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Deep sedation in pediatric imaging: efficacy and safety of intravenous chlorpromazine

Abstract: Intravenous chlorpromazine is safe and effective for procedural sedation in young children with cancer undergoing MRI and CT.

Cited by 14 publications

References 45 publications

Practice Advisory on Anesthetic Care for Magnetic Resonance Imaging

Practice Advisory on Anesthetic Care for Magnetic Resonance Imaging

Contrast-enhanced Magnetic Resonance Imaging in Pediatric Patients: Review and Recommendations for Current Practice

Sedation in pediatric magnetic resonance imaging: a ten-year experience

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