Deep Learning Powered Identification of Differentiated Early Mesoderm Cells from Pluripotent Stem Cells
Sakib Mohammad,
Arpan Roy,
Andreas Karatzas
et al.
Abstract:Pluripotent stem cells can be differentiated into all three germ-layers including ecto-, endo-, and mesoderm in vitro. However, the early identification and rapid characterization of each germ-layer in response to chemical and physical induction of differentiation is limited. This is a long-standing issue for rapid and high-throughput screening to determine lineage specification efficiency. Here, we present deep learning (DL) methodologies for predicting and classifying early mesoderm cells differentiated from… Show more
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