Deep-Learning-Guided Electrochemical Impedance Spectroscopy for Calibration-Free Pharmaceutical Moisture Content Monitoring
Guangshuai Han,
Brent Maranzano,
Christopher Welch
et al.
Abstract:The moisture content of pharmaceutical powders can significantly impact the physical and chemical properties of drug formulations, solubility, flowability, and stability. However, current technologies for measuring moisture content in pharmaceutical materials require extensive calibration processes, leading to poor consistency and a lack of speed. To address this challenge, this study explores the feasibility of using impedance spectroscopy to enable accurate, rapid testing of moisture content of pharmaceutica… Show more
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