2020
DOI: 10.1038/s41598-020-59801-x
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Deep learning for irregularly and regularly missing data reconstruction

Abstract: Deep learning (DL) is a powerful tool for mining features from data, which can theoretically avoid assumptions (e.g., linear events) constraining conventional interpolation methods. Motivated by this and inspired by image-to-image translation, we applied DL to irregularly and regularly missing data reconstruction with the aim of transforming incomplete data into corresponding complete data. to accomplish this, we established a model architecture with randomly sampled data as input and corresponding complete da… Show more

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Cited by 75 publications
(23 citation statements)
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“…Most of the statistical methods cannot be directly applied on an incomplete dataset due to their mathematical assumptions. Deep learning-based approaches can evaluate the datasets without doing preomit/impute missing value from dataset [ 37 ].…”
Section: Methodsmentioning
confidence: 99%
See 1 more Smart Citation
“…Most of the statistical methods cannot be directly applied on an incomplete dataset due to their mathematical assumptions. Deep learning-based approaches can evaluate the datasets without doing preomit/impute missing value from dataset [ 37 ].…”
Section: Methodsmentioning
confidence: 99%
“…x n keeps that units of continuous variables do not influence the (square) distance between individuals (Figure 2) [34,35]. [37].…”
Section: Famdmentioning
confidence: 99%
“…The presence of sparse features characterizes single-cell RNA-seq datasets due to experimental limitations [ 105 , 106 ]. Data reconstruction aims at transforming incomplete input values into a corresponding complete set [ 107 ]. Several reconstruction methods have been developed to overcome this technical heterogeneity of single-cell transcriptomic profiles.…”
Section: Managing the Heterogeneity Of Cancer Transcriptomesmentioning
confidence: 99%
“…Śmieja et al (2018) propose that missing data can be handled by replacing a neuron's response in the rst hidden layer by its expected value, thus proposing a neural/unit-level embodiment of Bengio & Gringras's proposal of using the unconditional mean. Chai et al (2020) ll gaps in a sparsely sampled dataset by tting curves to the data and interpolating.…”
Section: Current Thinking About Generalization In Learned Systemsmentioning
confidence: 99%