Deep eutectic solvent self-assembled reverse nanomicelles for transdermal delivery of sparingly soluble drugs
Bin Li,
Siwen Jiao,
Shiqi Guo
et al.
Abstract:Background
Transdermal delivery of sparingly soluble drugs is challenging due to their low solubility and poor permeability. Deep eutectic solvent (DES)/or ionic liquid (IL)-mediated nanocarriers are attracting increasing attention. However, most of them require the addition of auxiliary materials (such as surfactants or organic solvents) to maintain the stability of formulations, which may cause skin irritation and potential toxicity.
Results
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