Deep Eutectic Solvent-Mediated Synthesis of Spinel Zinc Chromite Nanoparticles: A Simple Label-Free Electrochemical Sensor for Dopamine and Ascorbic Acid

Abstract

Dopamine (DA) and ascorbic acid (AA) abnormal concentrations are intimately associated with many disorders, making the detection of these tiny molecules essential for keeping track of metabolic processes and preserving health. Due to its practicality from an economic standpoint, great sensitivity, and outstanding selectivity, electrochemical detection is a common technique for detecting tiny compounds. This technique's creation and use are equally crucial and cannot be disregarded. Due to their high surface-to-volume ratio and distinctive characteristics, nanomaterials are well-suited for various applications. In this study, we synthesized ZnCr 2 O 4 nanoparticles using an easy hydrothermal method. Given the difficulty of synthesizing nanoparticles and their importance in modern society, our research concentrated on this field. Based on statistical analysis, our results are consistent with the fabrication approach's anticipated results. This research aims to create electrochemical sensors that detect AA and DA in real time using ZnCr 2 O 4 nanocatalysts. The constructed sensor's oxidation potential is also significantly lower than that of recently published sensors of DA (E pa = 0.25 V) and AA (E pa = 0.45 V). In the concentration range of DA = 0.001−139 μM and AA = 0.01−126 μM, the suggested ZnCr 2 O 4 /GCE electrochemical sensing medium was used to detect AA and DA with great sensitivity. For AA and DA, the sensor demonstrated a detection limit of DA = 0.18 nM and AA = 12.56 nM. Furthermore, the ZnCr 2 O 4 /GCE sensor was an excellent tool for a technical feasibility study because the chosen possible interferences did not affect AA and DA sensing.

Fabrication of polypyrrole conductive matrix covered MnNi2O4 nanocomposite as a positive electrode material for asymmetric supercapacitor applications

“…The Warburg (W) diffusion element is exhibited by the slope of the line in the low-frequency zone. 33,38 The steeper slope of MnNi 2 O 4 /PPY showed a higher probability of ion diffusion compared to those of MnNi 2 O 4 and PPY. Further, the cyclic stability of the MnNi 2 O 4 /PPY electrode was evaluated at 10 000 GCD cycles at 3 A g −1 (Fig.…”

Highly Efficient Dopamine Sensing with a Carbon Nanotube-Encapsulated Metal Chalcogenide Nanostructure

“…The novelty of nonenzymatic electrochemical sensors is their direct detection method, which leads to higher sensitivity and low limit of detection. − However, to achieve such high-performance metrics, the use of an electrode modified with an electrocatalyst is critical. The electrocatalyst composition optimizes the electron transfer kinetics between the analyte–electrode interface, leading to selectivity in analyte detection, while the electrode–electrocatalyst composite is expected to facilitate charge transfer and increase sensitivity of the sensor.…”

Simultaneous recognition of dopamine and uric acid in real samples through highly sensitive new electrode fabricated using ZnO/carbon quantum dots: bio-imaging and theoretical studies

“…8 Generally, DA and UA are coexistent in the blood, and their rapid recognition is challenging in modern analytical chemistry. 9 Thus, the development of new techniques for the determination of the concentration of these analytes is vital, especially for their cost-effective measurement. 2,10 In this context, different analytical methods have been applied to improve the simplicity and sensitivity for the detection of DA and UA.…”