Deep dorsal penile vein thrombosis in a patient with COVID‐19 infection: A rare complication and the first reported case

Bagheri, Seyed Morteza; Tabrizi, Zhale

doi:10.1002/ccr3.5117

Cited by 5 publications

(4 citation statements)

References 23 publications

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“…Distinct from PMD, Peyronie's disease is characterized by subcutaneous sclerosing lesions with a distinctive curved shape and a history of penile trauma [ 32 ]. Additionally, two case reports have suggested a link between SARS-CoV-2 infection and PMD due to COVID-19's documented impact on thrombosis pathophysiology [ 33 - 35 ]. Moreover, in men with erectile dysfunction and a low International Index of Erectile Function (IIEF-5) score, PMD may exacerbate symptoms [ 41 ].…”

Section: Discussionmentioning

confidence: 99%

Penile Mondor's Disease Resulting From Forceful Condom Removal During Sexual Intercourse: A Case Report and Literature Review

Alzahrani

2023

Cureus

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Penile Mondor's disease, or dorsal vein thrombophlebitis, is vital for urologists to recognize. It causes pain and hardening in the penis due to triggers like trauma or neoplasms. Distinguishing it from similar conditions such as sclerosing lymphangitis and Peyronie’s disease is crucial. Penile Doppler ultrasound is the preferred diagnostic method. Providing reassurance can ease patient anxiety. This case report highlights a unique occurrence following forceful condom removal during sex, detailing symptoms, diagnosis, and successful treatment.

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Section: Discussionmentioning

confidence: 99%

Penile Mondor's Disease Resulting From Forceful Condom Removal During Sexual Intercourse: A Case Report and Literature Review

Alzahrani

2023

Cureus

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“…Deep network involvement can lead to penile pain, priapism, and even ischemia of the corpora cavernosa. The few cases reported in the literature were secondary to COVID-19 infection, prostate abscess, or factor VIIIa hypercoagulation [ 5 , 9 , 10 ].…”

Section: Discussionmentioning

confidence: 99%

“…The occurrence of venous thrombosis of the penis is often related to Mondor’s disease (superficial vein thrombosis). Several cases have been reported in the literature in recent years, while thrombosis of the deep dorsal vein of the penis has rarely been reported [ 5 ].…”

Section: Introductionmentioning

confidence: 99%

Thrombosis of the deep dorsal vein of the penis caused by vaccine-induced thrombotic thrombocytopenia: First reported case

Jamali

Cherraqi

Mvomo

et al. 2022

Arab Journal of Urology

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The first described case of deep dorsal vein thrombosis of the penis secondary to vaccine-induced thrombotic thrombocytopenia (VITT), a complication of COVID adenoviral vector vaccines. The patient reported pain in the penis one month after vaccination. On ultrasound, a deep dorsal vein thrombosis was found and a biological workup was ordered to confirm the VITT trail. Anticoagulant therapy was immediately initiated and the patient responds well while suffering from erectile dysfunction. VITT is a potentially serious event that can be life-threatening; every practitioner should know how to deal with it.

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“…Although the most common thrombotic state of COVID-19 infection is deep vein thrombosis and pulmonary embolism, so far published isolated reports indicate that it can also manifest itself as thrombosis of the penis vessels [ 16 – 18 ]. Furthermore, a report shows that past COVID-19 penile vessel thrombosis can appear not only as PMD, superficial thrombosis of the dorsal penile vein, but also as deep thrombosis of the dorsal penile vein or circumflex vein [ 17 , 19 ].…”

Section: Introductionmentioning

confidence: 99%

COVID-19 infection as a new risk factor for penile Mondor disease

et al. 2022

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Background Penile Mondor disease is a superficial dorsal vein thrombophlebitis of the penis, which mainly affects young and middle-aged men. It generally manifests as a visible painful cord located along the dorsal surface of the penis with signs of skin inflammation. The condition is usually self-limiting, but in severe cases a surgical procedure may be necessary in addition to pharmacological treatment. Coronavirus disease 2019 (COVID-19) caused by SARS-CoV-2 is associated with a frequent incidence of thrombophilia; therefore, such a prothrombotic state during infection may be a significant risk factor for penile Mondor disease. Case presentation The 34-year-old patient reported moderate pain felt on the surface of the penis. During the medical interview, the patient did not admit significant risk factors for Mondor Disease, apart from the previous, a month earlier COVID-19 disease. Examination revealed swelling erythema and a thick indurated cord on the surface of the penis. Color Doppler ultrasound was performed to confirm assumptions and exclude thrombosis of other penile vessels. Based on visible clots in the course of the superficial penile vein and after exclusion of vasculitis due to autoimmune disease the diagnosis of penile Mondor disease was made. Pharmacological therapy was implemented to further break down the clot and prevent rethrombosis in the penile vessels. The patient did not report any treatment complications and returned for a control visit, which revealed complete clot dissolution on ultrasound; therefore, complete recovery was stated. Conclusions This case report presents the correlation between SARS-Cov-2 infection and penile Mondor disease, based on the confirmed influence of COVID-19 on the pathophysiology of thrombosis. It can be concluded that COVID- 19 is a risk factor for Mondor disease, as in the presented case the virus was the only prothrombotic risk factor for the patient. Consequently, the possibility of developing thrombosis in the form of penile Mondor disease should be taken into account among patients with post-COVID-19 and active SARS-Cov-2 infection.

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Deep dorsal penile vein thrombosis in a patient with COVID‐19 infection: A rare complication and the first reported case

Abstract: This is an open access article under the terms of the Creat ive Commo ns Attri bution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

Cited by 5 publications

References 23 publications

Penile Mondor's Disease Resulting From Forceful Condom Removal During Sexual Intercourse: A Case Report and Literature Review

Penile Mondor's Disease Resulting From Forceful Condom Removal During Sexual Intercourse: A Case Report and Literature Review

Thrombosis of the deep dorsal vein of the penis caused by vaccine-induced thrombotic thrombocytopenia: First reported case

COVID-19 infection as a new risk factor for penile Mondor disease

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