Abstract:Background: In the distal left main (LM) atherosclerosis mainly develops within bifurcation or trifurcation. The aim of this study was to analyze the strategy of distal LM stenosis treatment and associated clinical outcomes in a large (BiOSS 12.5% vs. rDES 9.6%). In logistic regression for 36-month TLR rate proximal optimization technique (OR 0.311,) was a prognostic factor of better clinical outcome, whereas non-ST-elevation ACS (OR 2.211,, MACE and TLR rates. (Cardiol J 2018; 25, 2: 188-195)
“…Covering the SB ostium, which is facilitated by Stentys DES architecture, could decrease the need for second stent implantation. Indeed, the rate of SB stenting in the current study was low and comparable to other dedicated bifurcation DES such as Bioss LIM (Balton, Warsaw, Poland) . notwithstanding, it was lower than in other previously tested stents .…”
Background
There is a paucity of data on left main (LM) percutaneous coronary intervention (PCI) therapy with dedicated DES platforms. The LM‐STENTYS is a multicenter registry aimed at evaluating clinical outcome after PCI of LM performed with a self‐apposing Stentys DES implantation.
Methods
The registry consists of 175 consecutive patients treated with Stentys DES implanted to LM. The primary endpoint was the composite of major adverse cardiac and cerebral events (MACCE) defined as cardiac death, myocardial infarction (MI), target lesion revascularization (TLR), and stroke assessed after 1 year. The secondary endpoint was stent thrombosis (ST) at 1 year.
Results
The median age was 69 years (IQR, 62–78 years). Acute coronary syndrome (ACS) was the presenting diagnosis in 117 (66.9%) patients [74 (63.2%) unstable angina, 31 (26.5%) NSTEMI, 12 (10.3%) STEMI] and stable angina (SA) was present in 58 (33.1%) patients. The median SYNTAX score was 23.0 (IQR, 18.7–32.2) in the SA group and 25.0 (IQR, 20.0–30.7) in the ACS group. During 1‐year follow‐up in the SA group two (3.4%) MACCE occurred, both of them were cardiac deaths. In ACS patients there were 19 (16.2%) MACCE [9 (7.7%) cardiac deaths, 11 (9.4%) MIs, 11(9.4%) TLR, 1(0.9%) stroke]. Altogether, three (1.7%) cases of acute ST were noted, all of them in ACS subset.
Conclusion
LM PCI using self‐apposing Stentys DES showed favorable clinical outcomes at 1‐year in patients with SA. Events of ST in the ACS group warrant further research.
“…Covering the SB ostium, which is facilitated by Stentys DES architecture, could decrease the need for second stent implantation. Indeed, the rate of SB stenting in the current study was low and comparable to other dedicated bifurcation DES such as Bioss LIM (Balton, Warsaw, Poland) . notwithstanding, it was lower than in other previously tested stents .…”
Background
There is a paucity of data on left main (LM) percutaneous coronary intervention (PCI) therapy with dedicated DES platforms. The LM‐STENTYS is a multicenter registry aimed at evaluating clinical outcome after PCI of LM performed with a self‐apposing Stentys DES implantation.
Methods
The registry consists of 175 consecutive patients treated with Stentys DES implanted to LM. The primary endpoint was the composite of major adverse cardiac and cerebral events (MACCE) defined as cardiac death, myocardial infarction (MI), target lesion revascularization (TLR), and stroke assessed after 1 year. The secondary endpoint was stent thrombosis (ST) at 1 year.
Results
The median age was 69 years (IQR, 62–78 years). Acute coronary syndrome (ACS) was the presenting diagnosis in 117 (66.9%) patients [74 (63.2%) unstable angina, 31 (26.5%) NSTEMI, 12 (10.3%) STEMI] and stable angina (SA) was present in 58 (33.1%) patients. The median SYNTAX score was 23.0 (IQR, 18.7–32.2) in the SA group and 25.0 (IQR, 20.0–30.7) in the ACS group. During 1‐year follow‐up in the SA group two (3.4%) MACCE occurred, both of them were cardiac deaths. In ACS patients there were 19 (16.2%) MACCE [9 (7.7%) cardiac deaths, 11 (9.4%) MIs, 11(9.4%) TLR, 1(0.9%) stroke]. Altogether, three (1.7%) cases of acute ST were noted, all of them in ACS subset.
Conclusion
LM PCI using self‐apposing Stentys DES showed favorable clinical outcomes at 1‐year in patients with SA. Events of ST in the ACS group warrant further research.
“…The first BiOSS ® stent was a bare metal one (stainless steel), but shortly after, a paclitaxel-eluting version was introduced into the market -the BiOSS Expert ® stent (CE Mark 2010), and in 2012 the sirolimus-eluting BiOSS LIM ® stent was developed. The obtained results in registries and clinical trials [8][9][10][11][12][13] as well as in everyday practice were satisfactory [14][15][16], but still a means of improvement has been sought. Therefore, a cobalt-chromium sirolimus-eluting version has been developed, i.e.…”
Bifurcation treatment with a single dedicated bifurcation stent (BiOSS LIM C®) is feasible and highly successful (100% implantation success rate). The short-term clinical outcomes are very promising, also in distal left main stenosis. The 12-month observations are pending.
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