Decreasing Impact of Requiring Assistance Injecting on HIV Incidence

Lappalainen, Leslie; Hayashi, Kanna; Dong, Huiru; Wood, Evan

doi:10.1097/qai.0000000000000554

Cited by 6 publications

(6 citation statements)

References 13 publications

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“…We also found that receiving injection assistance alone was not significantly associated with either distributive or receptive syringe sharing. This finding differs significantly from prior studies where receiving injection assistance was associated with syringe sharing (Cheng et al, 2016;Lee et al, 2013;Pedersen et al, 2016;Robertson et al, 2010;, HIV infection, and HCV and HIV incidence (Lappalainen et al, 2015;Miller et al, 2002;Spittal et al, 2002). The lack of an association between receiving injection assistance and syringe sharing behaviors could be the result of three things.…”

Section: Discussioncontrasting

confidence: 95%

“…Among PWID interactions, peer-to-peer injection or the practice of giving (provider) or receiving injection assistance (recipient) from another PWID, is an important contributor to health outcomes in this population. Both forms of peer-to-peer injection have been associated with infectious disease risk and other harms related to drug injection including syringe sharing (Carlson, 2000;Fairbairn et al, 2006;Friedman et al, 2002;Kral, Bluthenthal, Erringer, Lorvick, & Edlin, 1999;Lee et al, 2013;Pedersen et al, 2016;Wood et al, 2001), abscesses and soft tissue infections (Lee et al, 2013;Lloyd-Smith et al, 2008), drug overdose (Fairbairn, Small, Van Borek, Wood, & Kerr, 2010), and HIV incidence (Lappalainen, Kerr, Hayashi, Dong, & Wood, 2015;O'Connell et al, 2005;Spittal et al, 2002).…”

Section: Introductionmentioning

confidence: 99%

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Peer-to-peer injection: Demographic, drug use, and injection-related risk factors

Lamb

Kral

Dominguez-Gonzalez

et al. 2018

International Journal of Drug Policy

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Background: Peer-to-peer injection (either providing or receiving an injection to/from a person who injects drugs [PWID]) is common (19%-50%) among PWID. Most studies of peer-to-peer injection have focused on receiving injection assistance, with fewer examining providing injection assistance and none considering characteristics of PWID who do both. We examined characteristics of PWID by peer-to-peer injection categories (receiving, providing, both, and neither) and determined if these behaviors were associated with receptive and distributive syringe sharing.Methods: Los Angeles and San Francisco PWID (N = 777) were recruited using targeted sampling methods and interviewed during 2011-2013. Multinomial logistic regression was used to determine characteristics associated with peer-to-peer injection categories and logistic regression was used to examine if peer-to-peer categories were independently associated with distributive and receptive syringe sharing.Results: Recent peer-to-peer injection was reported by 42% of PWID (18% provider; 14% recipient; 10% both). In multinomial regression analysis, PWID reporting any peer-to-peer injection were more likely to inject with others than those who did neither. Injection providers and those who did both were associated with more frequent injection, illegal income source, and methamphetamine injection while injection recipients were associated with fewer years of injection. Injection providers were younger, had more years of injecting, and were more likely to inject heroin than PWID who did neither. In multivariate analyses, we found that providers and *

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Section: Discussioncontrasting

confidence: 95%

Section: Introductionmentioning

confidence: 99%

Peer-to-peer injection: Demographic, drug use, and injection-related risk factors

Lamb

Kral

Dominguez-Gonzalez

et al. 2018

International Journal of Drug Policy

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“…While a recent study has suggested a declining impact of assisted injecting on HIV incidence in Vancouver [ 18 ], little is known about changes in the prevalence and the associated harms of assisted injection over time in this setting, and how they may differ across the genders. Therefore, we conducted a gender-based analysis among PWID in Vancouver to examine trends in the rates of requiring assisted injecting over time.…”

Section: Introductionmentioning

confidence: 99%

Declining trends in the rates of assisted injecting: a prospective cohort study

et al. 2016

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BackgroundAssisted injecting has been associated with increased risk of blood-borne infections, overdose, and other harms among people who inject drugs (PWID), particularly women. Given the changing availability of relevant harm reduction interventions in Vancouver, Canada, in recent years, we conducted a gender-based analysis to examine changes in rates and correlates of assisted injecting over time among active PWID.MethodsUsing data from a prospective cohort of PWID in Vancouver, we employed gender-stratified multivariable generalized estimating equations to examine trends in assisted injecting and identify the correlates during two periods: June 2006–November 2009 and December 2009–May 2014.ResultsAmong 1119 participants, 376 (33.6 %) were females. Rates of assisted injecting declined between 2006 and 2014 among males (21.9 to 13.8 %) and females (37.0 to 25.6 %). In multivariable analyses, calendar year of interview also remained independently and negatively associated with assisted injecting among males (adjusted odds ratio [AOR] 0.95, 95 % confidence interval [CI] 0.92–0.99) and females (AOR 0.93, 95 % CI 0.89–0.97). Syringe borrowing remained independently associated with assisted injecting throughout the study period among females (AOR 1.53, 95 % CI 1.10–2.11 during 2006–2009; AOR 2.15, 95 % CI 1.24–3.74 during 2009–2014) and during 2009–2014 among males (AOR 1.88, 95 % CI 1.02–3.48).ConclusionsOur findings demonstrate assisted injecting has significantly decreased for both males and females over the past decade. Nevertheless, rates of assisted injecting remain high, especially among women, and are associated with high-risk behavior, indicating a need to provide safer assisted injecting services to these vulnerable sub-populations of PWID.

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“…Daher hat die Frage nach Risikoverhalten bei sexuellen Aktivitä ten und im Umgang mit Injektionsnadeln in dieser Patienten gruppe weiterhin eine hohe klinische Relevanz. International gibt es mehrere Studien, welche das Risikoverhal ten bei opioidabhängigen Patienten untersucht haben, hierbei unterscheiden sich die Häufigkeiten von Infektionserkrankun gen aber zum Teil wesentlich von Prävalenzen in Deutschland [13,[17][18][19][20]. Zudem beziehen sich die Daten auf eine andere me dizinische Versorgungsstruktur, einschließlich Präventions aspekten, welche insbesondere bei Opioidsubstitution von hoher Relevanz sind.…”

Section: Einleitung ▼unclassified

“…Trotz Aufklärungsarbeit und Projekten zur Harm reduction bleiben körperliche Folgeerkrankun gen, vor allem chronische Infektionserkrankun gen, eines der Hauptprobleme in der Substitu tionsbehandlung opioidabhängiger Patienten [11][12][13]. Hierbei ist vor allem die Infektion mit Hepatitis C zu nennen [14,15].…”

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Risikoverhalten bei sexuellen Aktivitäten und im Umgang mit Injektionsnadeln bei opioidabhängigen Patienten in Substitutionstherapie

et al. 2016

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Zusammenfassung Ziel: Untersuchung von Risikoverhalten bei sexuellen Aktivit?ten und im Umgang mit Nadeln bei Patienten mit Opioidabh?ngigkeit in Substitutionstherapie (POS) im Vergleich zu Patienten mit anderen Substanzabh?ngigkeiten (PAS). Methode: Anonyme Befragung von 101 POS, sowie 99 PAS. Ergebnisse: POS berichten signifikant h?ufiger ?ber Hepatitis C- und B-Infektionen, Risikoverhalten bei sexuellen Aktivit?ten mit Personen mit Infektionserkrankungen und intraven?sem Konsum als PAS. H?ufiger ungesch?tzter Geschlechtsverkehr wird sowohl von POS als auch von PAS berichtet, ungesch?tzter Geschlechtsverkehr mit Gelegenheitspartner signifikant h?ufiger von PAS. Es zeigen sich zudem keine Unterschiede im Risikoverhalten zwischen POS mit und ohne Infektionserkrankungen. Schlussfolgerung: Relevantes Risikoverhalten findet sich sowohl bei POS als auch bei PAS. Von besonderer klinischer Relevanz ist es bei Patienten mit Infektionserkrankungen, welche durch ihr Risikoverhalten andere Personen gef?hrden k?nnen.

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Decreasing Impact of Requiring Assistance Injecting on HIV Incidence

Cited by 6 publications

References 13 publications

Peer-to-peer injection: Demographic, drug use, and injection-related risk factors

Peer-to-peer injection: Demographic, drug use, and injection-related risk factors

Declining trends in the rates of assisted injecting: a prospective cohort study

Risikoverhalten bei sexuellen Aktivitäten und im Umgang mit Injektionsnadeln bei opioidabhängigen Patienten in Substitutionstherapie

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