Decreased wall shear stress in the common carotid artery of patients with peripheral arterial disease or abdominal aortic aneurysm: Relation to blood rheology, vascular risk factors, and intima-media thickness

Spring, Silviana; Loo, Bernd van der; Krieger, Elisabeth; Amann-Vesti, Beatrice; Rousson, Valentin; Koppensteiner, Renate

doi:10.1016/j.jvs.2005.09.030

Cited by 31 publications

(29 citation statements)

References 28 publications

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“…Plasma viscosity was determined in ethylenediaminetetraacetic acid plasma by using a viscometer of the capillary type at 25 °C (Processer Viscosity System 1, Lauda, Germany). Whole blood viscosity was measured in ethylenediaminetetraacetic acid plasma using a rotational viscometer (Contraves LS 30, Contraves, Switzerland) at a high shear rate (94.5/s) at 37 °C (13). Peak and mean wall shear stress (dyn/cm 2 ) were calculated as previously described (13): shear stress = 4 × blood viscosity (P) × blood velocity (cm/s)/internal diameter of the main pulmonary artery (cm).…”

Section: Rheological Measurementsmentioning

confidence: 99%

Biomarker and shear stress in secondary pediatric pulmonary hypertension

Pektas¹,

Olguntürk²,

Kula³

et al. 2017

Turk J Med Sci

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Section: Rheological Measurementsmentioning

confidence: 99%

Biomarker and shear stress in secondary pediatric pulmonary hypertension

Pektas¹,

Olguntürk²,

Kula³

et al. 2017

Turk J Med Sci

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“…One study reported that CIMT values in patients with AAA and PAD increased at a similar rate to those of healthy volunteers (29). Studies maintaining the opposite, however, have reported similar CIMT values in patients with AAA to those in healthy volunteers but significantly lower values than those in patients with PAD (10,30).…”

Section: Discussionmentioning

confidence: 98%

The role of vascular elastography and carotid artery intima media thickness methods in the determination of non-syndromic ascending thoracic aortic aneurysm

Hemsinli¹,

Korkmaz²,

Baki³

et al. 2017

J Turgut Ozal Med Cent

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Aim:The role of atherosclerosis in the pathogenesis of ascending thoracic aortic aneurysms is still uncertain. Ultrasonic elastography is a new diagnostic method, the use of which has diversified considerably in recent years. An increase in intima media thickness in the carotid arteries is an early finding of atherosclerosis. Our purpose was to investigate the effect of atherosclerosis in the development of ascending thoracic aortic aneurysms and to be able to recommend a non-invasive and inexpensive scanning method aiming at early diagnosis. Material and Methods: Thirty-three patients with ascending thoracic aortic aneurysms (aTAA group) and 40 patients with normal measurement (control group) values were included in the study. The carotid artery intima media thicknessof carotid arteries were measured using B mode ultrasonography. Elastographic examination of the intima-media was then performed. Results: Body mass index, past smoking status, hypertension, presence of coronary artery disease and hyperlipidemia were higher in the aTAA group than in the control group (p<0.05). No significant difference was determined between these two groups' ultrasonic elastography or intima media thickness in the carotid arteries values (p<0.05). Conclusions: Our findings suggest that the effect of atherosclerosis in the pathogenesis of ascending thoracic aortic aneurysms is limited. Vascular ultrasonic elastography and intima media thickness determination in the carotid arteries appear not to be effective in the evaluation of ascending thoracic aortic aneurysms.

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“…WSS is associated with traditional risk factors, but only smoking, age and triglycerides remained significantly associated with this on multivariate analysis (146). An inverse relationship exists between WSS and carotid wall thickness has been reported (147).…”

Section: Wall Shear Stress (Wss)mentioning

confidence: 91%

Peripheral arterial disease and Virchow’s triad

Bennett

Silverman

Gill³

et al. 2009

Thromb Haemost

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SummaryPeripheral arterial disease (PAD) is an important global healthcare problem associated with considerable morbidity and mortality. This disease is an important manifestation of atherosclerosis and the pathophysiological processes involved in its development, progression and complications are atherothrombosis and thromboembolism. Over 150 years ago, Virchow described a triad of abnormalities (abnormal blood flow, abnormal vessel wall and abnormal blood constituents) associated with KeywordsArterial thrombosis, clinical studies, risk factors thrombus formation (thrombogenesis). An improvement in biochemical techniques has allowed quantification of various components of Virchow's triad, and as a consequence, there has been increasing interest in the measurement of such biomarkers in understanding the development and progression of PAD, as well as its symptomatic complications. This review discusses quantifiable components of Virchow's triad that have been associated with PAD and their clinical utility as risk factors for PAD.

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Decreased wall shear stress in the common carotid artery of patients with peripheral arterial disease or abdominal aortic aneurysm: Relation to blood rheology, vascular risk factors, and intima-media thickness

Abstract: This is the first report, to our knowledge, showing that wall shear stress of the common carotid artery is decreased in patients with symptomatic PAD and in patients with AAA. Rheologic variables are less important in predicting wall shear stress than age, triglycerides, and smoking.

Cited by 31 publications

References 28 publications

Biomarker and shear stress in secondary pediatric pulmonary hypertension

Biomarker and shear stress in secondary pediatric pulmonary hypertension

The role of vascular elastography and carotid artery intima media thickness methods in the determination of non-syndromic ascending thoracic aortic aneurysm

Peripheral arterial disease and Virchow’s triad

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