Decreased free D-aspartate levels in the blood serum of patients with schizophrenia
Martina Garofalo,
Giuseppe De Simone,
Zoraide Motta
et al.
Abstract:IntroductionSchizophrenia (SCZ) and autism spectrum disorder (ASD) are neurodevelopmental diseases characterized by different psychopathological manifestations and divergent clinical trajectories. Various alterations at glutamatergic synapses have been reported in both disorders, including abnormal NMDA and metabotropic receptor signaling.MethodsWe conducted a bicentric study to assess the blood serum levels of NMDA receptors-related glutamatergic amino acids and their precursors, including L-glutamate, L-glut… Show more
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