Decrease in TSH levels after lactose restriction in Hashimoto’s thyroiditis patients with lactose intolerance

Aşık, Mehmet; Güneş, Fahri; Binnetoğlu, Emine; Eroğlu, Mustafa; Bozkurt, Neslihan; Şen, Hacer; Akbal, Erdem; Bakar, Çoşkun; Beyazıt, Yavuz; Ükinç, Kubilay

doi:10.1007/s12020-013-0065-1

Cited by 43 publications

(44 citation statements)

References 22 publications

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“…In hypothyroidism, they may be less severe [ 34 ]. However, in treated hypothyroidism, there is some suggestion that lactose intolerance may interfere with proper therapy of the low thyroid state and lactose withdrawal may facilitate therapy [ 35 ]. The reasons for these discrepancies are not clear.…”

Section: Symptomatic Improvement With Regular Lactose Consumption mentioning

confidence: 99%

Adaptation to Lactose in Lactase Non Persistent People: Effects on Intolerance and the Relationship between Dairy Food Consumption and Evalution of Diseases

Szilagyi

2015

Nutrients

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Dairy foods contain complex nutrients which interact with the host. Yet, evolution of lactase persistence has divided the human species into those that can or cannot digest lactose in adulthood. Such a ubiquitous trait has differential effects on humanity. The literature is reviewed to explore how the divide affects lactose handling by lactase non persistent persons. There are two basic differences in digesters. Firstly, maldigesters consume less dairy foods, and secondly, excess lactose is digested by colonic microflora. Lactose intolerance in maldigesters may occur with random lactose ingestion. However, lactose intolerance without maldigestion tends to detract from gaining a clear understanding of the mechanisms of symptoms formation and leads to confusion with regards to dairy food consumption. The main consequence of intolerance is withholding dairy foods. However, regular dairy food consumption by lactase non persistent people could lead to colonic adaptation by the microbiome. This process may mimic a prebiotic effect and allows lactase non persistent people to consume more dairy foods enhancing a favorable microbiome. This process then could lead to alterations in outcome of diseases in response to dairy foods in lactose maldigesters. The evidence that lactose is a selective human prebiotic is reviewed and current links between dairy foods and some diseases are discussed within this context. Colonic adaptation has not been adequately studied, especially with modern microbiological techniques.

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Section: Symptomatic Improvement With Regular Lactose Consumption mentioning

confidence: 99%

Adaptation to Lactose in Lactase Non Persistent People: Effects on Intolerance and the Relationship between Dairy Food Consumption and Evalution of Diseases

Szilagyi

2015

Nutrients

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“…To our knowledge, it is the first time that a significantly increased prevalence of FM or LM has been demonstrated in euthyroid patients with HT. Simultaneously, Asik et al 32 describe a high frequency of LM in HT patients, but without having performed a specific case-control study.…”

Section: Discussionmentioning

confidence: 99%

Evidence of impaired carbohydrate assimilation in euthyroid patients with Hashimoto’s thyroiditis

et al. 2015

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“…Hashimoto's disease often requires elimination of dairy products containing lactose. Lactose intolerance is diagnosed in 75.9 % of the patients with HT [82]. This intervention is all the more important in people taking levothyroxine, as lactose intolerance reduces the bioavailability of the drug and enforces the use of higher doses, hence the patients taking it or patients with elevated TSH should perform a lactose tolerance test and eliminate it if necessary [83].…”

Section: Elimination Of Lactose a Diet Targeting The Treatment Ofmentioning

confidence: 99%

The importance of nutritional factors and dietary management of Hashimoto’s thyroiditis

Ihnatowicz¹,

Drywień²,

Wątor³

et al. 2020

Ann Agric Environ Med.

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Hashimoto (HT) is an autoimmune disease in which destruction of the thyroid occurs as a result of lymphocyte infiltration. It is caused by an increased level of titers of antibody against thyroid peroxidase (TPO) and thyroglobulin (TG). Because of that,in HT patients, changes are observed in the level and metabolism of thyroid hormones, which leads to unspecified physical and psychological symptoms. A high level of antibodies attacking thyroid antigens has been positively correlated with the symptoms. From the etiological point of view, the most important are genetic factors; however, environmental factors are necessary to provoke the immune system to attack until the process is over. Scientists indicate specified stress, toxification, microbiota dysbiosis and under-or over-nutrition, to name only a few. Dietotherapy of Hashimoto's is based on the proper nourishment of the body and regulation of the immune system by an anti-inflammatory diet. Observational and controlled trials have shown frequent nutrition deficiencies in HT patients. In literature, there is evidence for selenium, potassium, iodine, copper, magnesium, zinc, iron, vitamin A, C, D and B. The role of the proper level of protein intake, dietary fibre and unsaturated fatty acids, especially the n-3 family, has been indicated. HT patients should often eliminate lactose because of intolerance and interactions with levothyroxine and gluten because of possible interactions of gliadin with thyroid antigens. The article describes the nutrition factors of HT patients, and share nutrition recommendations for diet therapy.

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Decrease in TSH levels after lactose restriction in Hashimoto’s thyroiditis patients with lactose intolerance

Cited by 43 publications

References 22 publications

Adaptation to Lactose in Lactase Non Persistent People: Effects on Intolerance and the Relationship between Dairy Food Consumption and Evalution of Diseases

Adaptation to Lactose in Lactase Non Persistent People: Effects on Intolerance and the Relationship between Dairy Food Consumption and Evalution of Diseases

Evidence of impaired carbohydrate assimilation in euthyroid patients with Hashimoto’s thyroiditis

The importance of nutritional factors and dietary management of Hashimoto’s thyroiditis

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