Decrease in the matrix effect of GC/MS by a gold-plated ion source

Abstract

The matrix effect is often observed when trace levels of pesticides in agricultural products are analyzed by GC/MS. In this study, we created a gold-plated ion source that included an ion source body, a draw-out plate lens, and an interface socket. When agricultural products fortified with a pesticide at 100 ppb were tested by GC/MS equipped with a gold-plated ion source, the matrix effect was reduced. The rates of decrease in the matrix effect value in samples of potato, spinach, orange brown rice, and soybean were 2.3%, 14%, 20%, 38%, and 15%, respectively. The rate of decrease was especially significant in the sample of brown rice. This result showed that the gold-plated ion source effectively reduced the interaction between the food matrix and the ion source.

Analysis of Cannabinoids in Biological Specimens: An Update

“…The result is an increased signal of the analyte in this case when compared to cases in which there are no interferents, which can overestimate cannabinoids' concentrations. There are some reported solutions to deal with this, but they demand a laborious sample treatment process [50] and modifications to the equipment [51], can easily lead to column deterioration, and present limited effectiveness [52].…”

Matrix Behavior during Sample Preparation Using Metabolomics Analysis Approach for Pesticide Residue Analysis by GC-MS in Agricultural Products

“…19,20 The matrix effect is caused by the adsorption of the pesticides on the active sites in the injection port, 11,13 column, and ion source. 21 Meanwhile, a metabolomics analysis is the metabolic profiling of metabolites from polar compounds, such as sugars, organic acids, and amino acids, to mid-low polar compounds, such as fatty acids and sterols in cells of all organisms (e.g., plants, humans, microbes). For all of these compounds, GC-MS is one of the most popular techniques because GC-MS is a robust and highly sensitive method with many databases.…”

“…These phenomena cause difficulty in the accurate quantification of the pesticides. Although GC-MS/MS has been widely used for its selectivity in the past few years, the matrix enhancement effect remains. , The matrix effect is caused by the adsorption of the pesticides on the active sites in the injection port, , column, and ion source …”