Decrease in LDL and increase in HDL concentrations in type II hyperlipoproteinaemic patients on low-dose combination therapy of cholestyramine and Complamin®

Fears, Robin; Ferres, H.; Haacke, H; Mäder, Ch.; Parwaresch, M. R.

doi:10.1016/0021-9150(88)90001-9

Atherosclerosis

1988

DOI: 10.1016/0021-9150(88)90001-9

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Decrease in LDL and increase in HDL concentrations in type II hyperlipoproteinaemic patients on low-dose combination therapy of cholestyramine and Complamin®

Robin Fears

H. Ferres

H Haacke³

et al.

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Cited by 4 publications

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Polycationic salts. VI. Synthesis and in vitro studies of 2‐ionene oligomer derivatives of styrene as bile acid sequestering agents

Zarras

2003

J. Polym. Sci. A Polym. Chem.

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Several vinylbenzyltri‐n‐alkylammonium salts were prepared via the Menshutkin reaction in high yields by the reaction of vinyl benzyl chloride (VBC) and tertiary amines. Additional salts based on 2‐ionene oligomers were synthesized via a sequential Menshutkin reaction. The 2‐ionene oligomers were further reacted with VBC to afford the vinyl benzyl chloride‐2‐ionene halide monomers in nearly quantitative yield. The monomers were polymerized in either aqueous or organic solvents with azo initiators in high yield with correspondingly high inherent viscosities. The polymers were measured spectrophotometrically for their bile acid sequestering activity with an in vitro enzymatic reaction. Several of the measured polymers exhibited 15–28% greater activity relative to cholestyramine. © 2003 Wiley Periodicals, Inc. J Polym Sci Part A: Polym Chem 42: 701–713, 2004

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Polycationic salts. VI. Synthesis and in vitro studies of 2‐ionene oligomer derivatives of styrene as bile acid sequestering agents

Zarras

2003

J. Polym. Sci. A Polym. Chem.

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Effects of novel bile salts on cholesterol metabolism in rats and guinea-pigs

Fears

Brown

Ferres

et al. 1990

Biochemical Pharmacology

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Polycationic salts as bile acid sequestering agents

Zarras

Vogl

1999

Progress in Polymer Science

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Decrease in LDL and increase in HDL concentrations in type II hyperlipoproteinaemic patients on low-dose combination therapy of cholestyramine and Complamin®

Cited by 4 publications

References 11 publications

Polycationic salts. VI. Synthesis and in vitro studies of 2‐ionene oligomer derivatives of styrene as bile acid sequestering agents

Polycationic salts. VI. Synthesis and in vitro studies of 2‐ionene oligomer derivatives of styrene as bile acid sequestering agents

Effects of novel bile salts on cholesterol metabolism in rats and guinea-pigs

Polycationic salts as bile acid sequestering agents

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