Decompressed percutaneous vertebroplasty: A secured bone cement delivery procedure for vertebral augmentation in osteoporotic compression fractures

Wu, Chu; Tsuei, Yu Chuan; Liao, Pei Hung; Lin, Jui Che; Chou, Wen Hsiang; Chu, Woei Chyn; Young, Shuenn Tsong

doi:10.1016/j.injury.2012.10.017

Cited by 15 publications

(21 citation statements)

References 40 publications

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“…High-viscosity PMMA, on the other hand, effectively stabilizes vertebral compression fractures, while minimizing the risk of cement leakage and associated complications in vitro [14,15]. Subsequently, decompressed PVP may result in reduced cement leakage [16]. Nieuwenhuijse et al performed a detailed analysis of potential risk factors for the occurrence of cement leakage, and fracture severity and PMMA bone cement viscosity were identified as two strong independent predictors in general [17].…”

Section: Cement Leakagementioning

confidence: 99%

A Review of PMMA Bone Cement and Intra‐Cardiac Embolism

et al. 2016

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Percutaneous vertebroplasty procedure is of major importance, given the significantly increasing aging population and the higher number of orthopedic procedures related to vertebral compression fractures. Vertebroplasty is a complex technique involving the injection of polymethylmethacrylate (PMMA) into the compressed vertebral body for mechanical stabilization of the fracture. Our understanding and ability to modify these mechanisms through alterations in cement material is rapidly evolving. However, the rate of cardiac complications secondary to PMMA injection and subsequent cement leakage has increased with time. The following review considers the main effects of PMMA bone cement on the heart, and the extent of influence of the materials on cardiac embolism. Clinically, cement leakage results in life-threatening cardiac injury. The convolution of this outcome through an appropriate balance of complex material properties is highlighted via clinical case reports.

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Section: Cement Leakagementioning

confidence: 99%

A Review of PMMA Bone Cement and Intra‐Cardiac Embolism

et al. 2016

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“…High-viscosity PMMA, on the other hand, effectively stabilizes vertebral compression fractures, while minimizing the risk of cement leakage and associated complications in vitro [14,15]. Subsequently, decompressed PVP may result in reduced cement leakage [16]. Nieuwenhuijse et al performed a detailed analysis of potential risk factors for occurrence of cement leakage and fracture severity and PMMA bone cement viscosity were identified as two strong independent predictors in general [17].…”

Section: Factors Affecting Cement Leakagementioning

confidence: 99%

A Review of PMMA Bone Cement and Intra-Cardiac Embolism

Shridhar¹,

Chen²,

Khalil³

et al. 2016

Preprint

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Percutaneous vertebroplasty procedure is of major importance, given the significant increasing aging population and higher number of orthopedic procedures related to vertebral compression fractures. Vertebroplasty is a complex technique involving injection of polymethylmethacrylate (PMMA) into the compressed vertebral body for mechanical stabilization of the fracture. Our understanding and ability to modify these mechanisms through alterations in cement material is rapidly evolving. However, the rate of cardiac complications secondary to PMMA injection and subsequent cement leakage has increased with time. The following review considers the main features of PMMA bone cement on the heart, and the extent of influence of materials on cardiac embolism. Clinically, cement leakage results in life-threatening cardiac injury. The convolution of this outcome through an appropriate balance of complex material properties is highlighted via clinical case report.

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“…[9–11] When PVP is done for VCFs, increasing amounts of bone cement have often needed to be injected into vertebrae, resulting in higher incidence of complications, including cement extravasation. [12,13] However, several studies have shown that a lower volume of bone cement could be injected while still achieving a satisfactory analgesic effect. [14,15] Indeed, Kaufmann et al [14] and Nieuwenhuijse et al [15] both reported that the volume of injected bone cement was not obviously correlated with pain relief.…”

Section: Discussionmentioning

confidence: 99%

Influence of vertebral bone mineral density on total dispersion volume of bone cement in vertebroplasty

Liu²,

Luo

et al. 2019

Medicine

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The aim of this study was to investigate the influence of vertebral bone mineral density (BMD) on total diffusion volume of bone cement in percutaneous vertebroplasty (PVP). This study was a retrospective review of prospectively collected data of consecutive patients with A1.2 thoracolumbar compression fractures treated by PVP. Vertebral BMD was measured before surgery and participants were divided into 3 groups according to World Health Organization diagnostic criteria for osteoporosis: Group A (normal BMD), Group B (reduced BMD), and Group C (osteoporosis). All vertebrae were injected with 3 mL of bone cement via the unilateral pedicle and scanned by computed tomography after surgery. Actual injection volume (bone cement only) and total diffusion volume (bone cement plus trabeculae and space) were calculated. Pain severity was determined by the visual analog scale before surgery and at both 1 day and 1 month after surgery. There were no significant differences in injection volume among the groups ( P > .05), but the total dispersion volume was greater than injection volume in all groups ( P < .05). Pairwise comparison showed a significant difference in total diffusion volume of bone cement between groups, with Group A having the largest volume and Group C the smallest volume. Pain was significantly reduced 1 day after surgery in each group compared with before surgery, but there were no significant between-group differences at 1 day or 1 month. Increasing vertebral BMD was positively correlated with increasing total diffusion volume. BMD does not significantly affect pain relief, despite producing a significantly lower distribution volume in osteoporotic patients.

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Decompressed percutaneous vertebroplasty: A secured bone cement delivery procedure for vertebral augmentation in osteoporotic compression fractures

Cited by 15 publications

References 40 publications

A Review of PMMA Bone Cement and Intra‐Cardiac Embolism

A Review of PMMA Bone Cement and Intra‐Cardiac Embolism

A Review of PMMA Bone Cement and Intra-Cardiac Embolism

Influence of vertebral bone mineral density on total dispersion volume of bone cement in vertebroplasty

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