“…In the last ten years, atmospheric-pressure plasmas have emerged as a competitive alternative to other methods of enhancing seed and seedling vigor and disease resistance, with the potential to combine efficacy, low cost, speed, simplicity, one-step processing, and low impact on human health and environment 2 – 5 . Initially building on advances in plasma-assisted material fabrication 6 – 9 , 10 , exhaust gas purification 11 , and wastewater treatment 12 , 13 , significant progress has been made in the use of plasmas to selectively induce apoptosis in cancer cells 14 – 16 , to eliminate bacterial biofilms on living surfaces and promote wound healing 17 , 18 , for pathogenic microorganism inactivation and removal from solid and liquid media 19 , 20 , for mutation breeding 21 and for agricultural production 4 , 22 , 23 . The unique advantage of using plasmas over other methods of biological stimulation stems from its multi-modal activity, specifically the simultaneous production of chemical species, including reactive oxygen species (ROS) and reactive nitrogen species (RNS) noted for their catalytic activity and biological significance, highly-energetic electrons, electromagnetic radiation and thermal effects, which individually and synergistically affect the treated target 24 , 25 .…”