Declining incidence of eyelid cancers in Singapore over 13 years: population-based data from 1996 to 2008

Abstract

The annual age-standardised incidence rates for male and female residents showed a steady decline over the last 13 years. These data suggest that factors related to sun protection have resulted in reduced eyelid cancers over time and provide a basis for such public health programmes elsewhere.

Cutaneous sebaceous carcinoma

“…Sebaceous carcinoma most frequently occurs in the age range 60 to 79 years but cases have been reported from 15 to 105 years . A higher proportion of all sebaceous carcinoma occurs in males than females (58–60%), whereas a higher proportion of ocular sebaceous carcinoma occurs in females (51–70%) …”

“…Sebaceous carcinoma most frequently occurs in the age range 60 to 79 years but cases have been reported from 15 to 105 years. [1][2][3]5 A higher proportion of all sebaceous carcinoma occurs in males than females (58-60%), whereas a higher proportion of ocular sebaceous carcinoma occurs in females (51-70%). 1,3,5,6 US data found a higher incidence rate for whites (0.23 per 100 000 person-years) than blacks (0.07 per 100 000, P < 0.01).…”

“…3 Similarly, the incidence rate in the predominantly Chinese populations of Taiwan and Singapore was 0.02-0.05 per 100 000 person-years. 2,6 The incidence rate of all sebaceous carcinoma has not been reported using prospective registry-based data from large Asian populations.…”

“…The cutaneous malignancy sebaceous carcinoma can occur anywhere on the skin but most often presents on the head and neck . It is the second or third most common eyelid malignancy depending on geographic area and is frequently misdiagnosed . Sebaceous carcinoma has a propensity to recur and metastasise, particularly if treated inadequately .…”

“…1 It is the second or third most common eyelid malignancy depending on geographic area and is frequently misdiagnosed. 2,3 Sebaceous carcinoma has a propensity to recur and metastasise, particularly if treated inadequately. 4 This article reviews its epidemiology, clinical features, histopathologic features, pathogenesis and management.…”