Decline in Perinatal Mortality in the United States, 2017–2019

Valenzuela, Claudia; Gregory, Elizabeth C W; Martin, Joyce

doi:10.15620/cdc:112643

Cited by 8 publications

(11 citation statements)

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“…This increase in the survival rates of children with extremely low body weight and very low body weight in Ukraine indicates the development of regionalization of perinatal care and the effectiveness of perinatal centers launched in 2010-2014 and is in line with global trends [1,4,21,22,24].…”

Section: Years Totalmentioning

confidence: 85%

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Birth rate, perinatal mortality and infant mortality in Ukraine: evolution from 1991 to 2021 and current risks

Волосовец

Abaturov²,

Бекетова

et al. 2023

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Ukraine is one of the poorest countries in Europe and currently is under attack of Russian troops. In recent decades, birth rate in Ukraine has been steadily declining by 47 %, and infant and perinatal mortality rates remain among the highest positions in Europe. Infant mortality, perinatal mortality, early neonatal mortality, and stillbirth rates in Ukraine have more than halved in 30 years and are lower than in the CIS countries, but still exceed those in the European Union. There is a downward trend in characteristics of all components of perinatal mortality; more for intranatal mortality, less for early neonatal mortality, whose share in the structure has increased in recent years, which requires improving the quality of medical care for newborns and taking measures for antenatal protection of the fetus. The fact that early neonatal mortality rates in Ukraine may be underestimated due to shortcomings in the registration of live births and stillbirths is worrying. Congenital malformations and conditions that appeared during pregnancy and childbirth in women who give birth to children with very low and extremely low body weight dominate among the causes of perinatal mortality in Ukraine. An effective way to reduce child losses in Ukraine during the last decade was the introduction of modern perinatal technologies to prevent pathological conditions in mothers and babies with extremely low and very low body weight, the continuation of the creation and restoration of a network of perinatal centers and proper conditions for safe childbirth in the regions of the country with the help of international aid, timely diagnosis and treatment of conditions that occur in the perinatal period and congenital malformations. An important resource for reducing infant and perinatal mortality in Ukraine and increasing the birth rate will be the stabilization of the sociopolitical situation in the country and appropriate international assistance in restoring the health care system, aimed at improving both somatic and reproductive health of future parents, especially mothers, forming in them a conscious and proper attitude to parenthood and care for the newborn.

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Section: Years Totalmentioning

confidence: 85%

“…Social protection of the population, age of mothers, birth rate, perinatal mortality, and quality of medical care for mothers and children are interconnected and interdependent things [1,4,16,24].…”

Section: Introductionmentioning

confidence: 99%

Birth rate, perinatal mortality and infant mortality in Ukraine: evolution from 1991 to 2021 and current risks

Волосовец

Abaturov²,

Бекетова

et al. 2023

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“…Due to variability of follow-up durations, neonatal survival is defined to match the definition of perinatal mortality defined by the National Center for Health Statistics. 13 Perinatal mortality was defined as the WALSH ET AL.…”

Section: Methodsmentioning

confidence: 99%

“…The t ‐test was used to compare GA at delivery between cases with and without antenatal treatment. Due to variability of follow‐up durations, neonatal survival is defined to match the definition of perinatal mortality defined by the National Center for Health Statistics 13 . Perinatal mortality was defined as the sum of infant deaths that occurred at less than 28 days of age and fetal deaths with a GA of 20 weeks or more.…”

Section: Methodsmentioning

confidence: 99%

Successful antenatal treatment of MAGED2‐related Bartter syndrome and review of treatment options and efficacy

Walsh,

Micke,

Elfman

et al. 2023

Prenatal Diagnosis

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A new form of transient antenatal Bartter syndrome (aBS) was recently identified that is associated with the X‐linked MAGED2 variant. Case reports demonstrate that this variant leads to severe polyhydramnios that may result in preterm birth or pregnancy loss. There is limited but promising evidence that amnioreductions may improve fetal outcomes in this rare condition. We report a woman with two affected pregnancies. In the first pregnancy, the patient was diagnosed with mild‐to‐moderate polyhydramnios in the second trimester that ultimately resulted in preterm labor and delivery at 25 weeks with fetal demise. Whole exome sequencing of the amniotic fluid sample resulted after the pregnancy loss and revealed a c.1337G>A MAGED2 variant that was considered diagnostically. The subsequent pregnancy was confirmed by chorionic villi sampling to also be affected by this variant. The pregnancy was managed with frequent ultrasounds and three amnioreductions that resulted in spontaneous vaginal delivery at 37 weeks and 6 days of a viable newborn with no evidence of overt electrolyte abnormalities suggesting complete resolution. A detailed review of the published cases of MAGED2‐related transient aBS is provided. Our review focuses on individuals who received antenatal treatment. A total of 31 unique cases of MAGED2‐related transient aBS were compiled. Amnioreduction was performed in 23 cases and in 18 cases no amnioreduction was performed. The average gestational age at delivery was significantly lower in cases without serial amnioreduction (28.7 vs. 30.71 weeks, p = 0.03). Neonatal mortality was seen in 5/18 cases without serial amnioreduction, and no mortality was observed in the cases with serial amnioreduction. In cases of second trimester severe polyhydramnios without identifiable cause, whole exome sequencing should be considered. Intensive ultrasound surveillance and serial amnioreduction is recommended for the management of MAGED2‐related transient aBS.

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“…Perinatal mortality is at its lowest [ 1 ] due to a series of factors, among which: Superior antenatal, and intrapartum, care, periodic ultrasound monitoring, and assessment of the fetus, placenta, and regular fetal heart rate monitoring. Fetal heart rate (performed either through auscultation or electronically) is essential in the assessment and prediction of fetal oxygenation and acid-base status [ 2 ], allowing the clinician to evaluate the status of the fetus before deciding on the course of action.…”

Section: Introductionmentioning

confidence: 99%

Current Innovative Methods of Fetal pH Monitoring—A Brief Review

Bohîlțea

Mihai²,

Ducu³

et al. 2022

Diagnostics

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In this study, we explore the “why?”, and “how?”, monitoring the pH of the fetal scalp is used, and show its limitations. In addition, we review the development of new devices based on the modern physics and nanomaterials serving this topic. Most of the works we found in our search have focused on improving the prognostic of fetal heart rate monitoring, because it is the “golden standard” in determining fetal distress. Although the best-known screening method, it can only provide limited information about the actual status of the fetus. The best predictive assessment, with the highest reproducibility, states that a normal fetal heart rate is indicative of a healthy baby. However, its excellent sensitivity is much reduced when identifying the actual “distress”. This is when second-line monitoring methods come into play to guide the diagnostics and direct the obstetrician towards an action plan. Although a historic method, fetal scalp pH sampling is still under review as to its efficiency and place in the current obstetrics. Continuous surveillance of the fetal parameters is important, especially for the fetuses undergoing intrauterine growth restricted (IUGR). Since fetal scalp blood sampling is still under research and is a randomized controlled trial, which compares the relevance of pH and lactates to the obstetrical situation, the maternal-fetal medicine could greatly benefit from the introduction of engineered nanomedicines to the field.

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Decline in Perinatal Mortality in the United States, 2017–2019

Abstract: This report presents trends in perinatal mortality, as well as its components, late fetal and early neonatal mortality, for 2017 through 2019. Also shown are perinatal mortality trends by mother’s age, race and Hispanic origin, and state for 2017–2019.

Cited by 8 publications

References 0 publications

Birth rate, perinatal mortality and infant mortality in Ukraine: evolution from 1991 to 2021 and current risks

Birth rate, perinatal mortality and infant mortality in Ukraine: evolution from 1991 to 2021 and current risks

Successful antenatal treatment of MAGED2‐related Bartter syndrome and review of treatment options and efficacy

Current Innovative Methods of Fetal pH Monitoring—A Brief Review

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