“…The objective of the technoeconomic evaluation was to quantify the performance of the alternative process configurations. First, the total capital investment required for each biorefinery configuration was calculated by collecting and scaling the reference cost and capacity of each piece of equipment using the I-BIOREF software developed by CanmetENERGY Centre of Natural Resources Canada and published references. ,, The reference costs were also updated to 2019 values using the chemical engineering plant cost index (CEPCI) as shown in eq , where superscript x refers to the equipment-dependent scaling exponent that ranged between 0.6 and 0.8. All the equipment was conventional, except for the membrane filtration system for which a separate costing approach was required. On the basis of the purchased equipment costs, multiplier factors were used to estimate the additional direct cost (piping, electrical, instrumentation and controls, installed buildings, process and auxiliary, service facilities, yard improvement, and capital spares) and the indirect costs (engineering and supervision, construction expense and contractor’s fee, legal expenses, and contingency).…”