Decision making in anomalous aortic origin of a coronary artery

Agrawal, Hitesh; Lamari-Fisher, Alexandra; Hasbani, Keren; Philip, Stephanie; Fraser, Charles D.; Mery, Carlos M.

doi:10.1080/14779072.2023.2184799

Cited by 4 publications

(2 citation statements)

References 74 publications

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“…Of all, some confer a high degree of cardiovascular risk. The "S" patterns, for example, usually require surgical intervention based on anatomy individually (7). For the right SCA, at present,15 cases with R-I are currently reported in the literature (8).…”

Section: Discussionmentioning

confidence: 99%

Case Report: A rare case of anomalous origin of the left coronary artery from the right coronary artery accompanied by left ventricular dysfunction in a young man

Tu,

Zhang,

Wang

et al. 2023

Preprint

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Single coronary artery (SCA) is a rare congenital malformation. In this case report, we present the admission of a young man to our department for the establishment of an antihypertensive program. The physical examination and lab tests did not reveal any obvious abnormalities. However, we found an absent left coronary ostium and a normal right coronary artery (RCA), which branched off the left coronary artery to supply the left heart. Further investigations including coronary computed tomography angiography (CCTA) and coronary angiography ruled out coronary heart disease. Transthoracic echocardiography revealed severe left ventricular dysfunction. Through the implementation of effective drug therapy, the blood pressure met the recommended standard and the young man remained in good clinical condition during follow-up.

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Section: Discussionmentioning

confidence: 99%

Case Report: A rare case of anomalous origin of the left coronary artery from the right coronary artery accompanied by left ventricular dysfunction in a young man

Tu,

Zhang,

Wang

et al. 2023

Preprint

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“…This dynamic proximal compression of the coronary may lead to a reduction of oxygenated blood supply to the heart during effort that can trigger adverse events such as SCD [4]. Clinical evaluations are based on anatomical assessment and myocardial functional testing [11]. Diagnosis and morphological evaluation are routinely performed with computed tomography angiography (CTA), which allows the definition of anomalous coronary anatomical features.…”

Section: Introductionmentioning

confidence: 99%

Assessment of Intramural Segment Compression in Anomalous Coronary Arteries through Patient-Specific Finite Element Modeling

Rosato,

Lo Rito,

Anglese

et al. 2023

Applied Sciences

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Background: Anomalous Aortic Origin of a Coronary Artery (AAOCA) is a congenital condition that can lead to ischemia and sudden cardiac death. Current diagnostic tools are unable to fully quantify the pathological behavior that occurs mainly with physical effort. Methods: Patients’ computed tomography scans and centerline-based geometric quantities were used to develop three-dimensional computer-aided design models of the main anatomical variants of AAOCA. Blood pressure ranging from rest to extreme effort was simulated through structural finite element analyses, and the pressurized geometries were analyzed to evaluate coronary lumen cross-sectional areas and variations at the different loading conditions. Results: We simulated 39 subjects, demonstrating the ability to reproduce accurately the patient-specific anatomy of different AAOCA variants and capture pathological behaviors. AAOCAs with intramural courses showed compression along the proximal segment with a caliber reduction ranging from 0.14% to 18.87% at different pressure levels. The percentage of proximal narrowing relative to the distal segment was greater than any other type of anomalous course and exceeded 50% with simulated exertion. Conclusions: The present study proposes a computational pipeline to investigate conditions not reproducible in clinical practice, providing information to support decision-making in the management of AAOCA patients.

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Management of Adults With Anomalous Aortic Origin of the Coronary Arteries: State-of-the-Art Review

Gaudino,

Di Franco,

Arbustini

et al. 2023

The Annals of Thoracic Surgery

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Decision making in anomalous aortic origin of a coronary artery

Cited by 4 publications

References 74 publications

Case Report: A rare case of anomalous origin of the left coronary artery from the right coronary artery accompanied by left ventricular dysfunction in a young man

Case Report: A rare case of anomalous origin of the left coronary artery from the right coronary artery accompanied by left ventricular dysfunction in a young man

Assessment of Intramural Segment Compression in Anomalous Coronary Arteries through Patient-Specific Finite Element Modeling

Management of Adults With Anomalous Aortic Origin of the Coronary Arteries: State-of-the-Art Review

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