Deciphering the functional role of insular cortex stratification in trigeminal neuropathic pain
Jaisan Islam,
Md Taufiqur Rahman,
Elina KC
et al.
Abstract:Trigeminal neuropathic pain (TNP) is a major concern in both dentistry and medicine. The progression from normal to chronic TNP through activation of the insular cortex (IC) is thought to involve several neuroplastic changes in multiple brain regions, resulting in distorted pain perception and associated comorbidities. While the functional changes in the insula are recognized contributors to TNP, the intricate mechanisms underlying the involvement of the insula in TNP processing remain subjects of ongoing inve… Show more
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