Decimals in data values

Stefánsson, Einar; Stefánsson, Gunnar; Sigurðsson, Sven; Briem, Eggert

doi:10.1111/j.1600-0420.2006.00725.x

Cited by 5 publications

(4 citation statements)

References 5 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…A total of 60 patients completed the entire study; their results are reported (Table 1). The results are presented in accordance with suggestions made in a previous publication (Stefansson et al. 2006).…”

Section: Methodssupporting

confidence: 91%

Comparison of the effects of travoprost, latanoprost and bimatoprost on ocular circulation: a 6‐month clinical trial

Köz

Özsoy

Yarangümeli

et al. 2007

Acta Ophthalmologica Scandinavica

View full text Add to dashboard Cite

ABSTRACT.Purpose: To study the effect of three prostaglandin F 2 -a (PG) analogues on retrobulbar blood flow velocity in previously untreated patients with primary open-angle glaucoma (POAG) or ocular hypertension (OHT), using colour Doppler ultrasound. Methods: Sixty newly diagnosed patients with POAG or OHT were randomly assigned to travoprost 0.004% (n ¼ 12 with POAG, n ¼ 8 with OHT), latanoprost 0.005% (n ¼ 11 with POAG, n ¼ 9 with OHT) and bimatoprost 0.03% (n ¼ 13 with POAG, n ¼ 7 with OHT) treatment groups in a double-masked fashion. At baseline examination, blood pressure, heart rate and intraocular pressure (IOP) were recorded. Peak-systolic and end-diastolic velocities were measured in the ophthalmic (OA), central retinal (CRA) and temporal short posterior ciliary arteries (PCA). The resistive index (RI) and ocular perfusion pressure (OPP) were determined for each treatment group. After a treatment period of 6-months, all procedures were repeated. Results: There were no significant differences in age (53 ± 14 years in the travoprost group, 51 ± 14 years in the latanoprost group, 53 ± 11 years in the bimatoprost group), gender (11 men, nine women; 11 men, nine women; 13 men, seven women, by group, respectively), or clinical diagnosis (POAG or OHT) among treatment groups (p > 0.05). A significant decrease in IOP (baseline: 26.4 ± 3.3 mmHg, 26.8 ± 1.3 mmHg, 25.8 ± 1.8 mmHg, respectively; month 6: 20.9 ± 1.9 mmHg, 20.8 ± 2.4 mmHg, 18.3 ± 1.2 mmHg, respectively; p < 0.0001) and an increase in OPP (baseline: 33.7 ± 3.8 mmHg, 33.5 ± 3.2 mmHg, 33.9 ± 2.6 mmHg, respectively; month 6: 40.2 ± 3.5 mmHg, 39.9 ± 3.1 mmHg, 41.7 ± 2.6 mmHg, respectively; p < 0.0001) were verified in all three groups during the study period. Mean baseline RI values for the CRA in the travoprost group and the OA in the latanoprost group were both 0.7 ± 0.1 mmHg and both values were statistically significantly lower at 6 months (0.6 ± 0.1 mmHg in both groups; p ¼ 0.002, p < 0.0001, respectively). In the bimatoprost group there was no statistically significant difference in haemodynamic parameters over the study period (p > 0.05). Conclusions: Our results suggest that the three PG analogues significantly reduce IOP and increase OPP in patients with POAG or OHT. Topical travoprost and latanoprost significantly reduce the RI of the CRA and OA, respectively. We were unable to determine any effect of topical bimatoprost on ocular haemodynamics.

show abstract

Section: Methodssupporting

confidence: 91%

Comparison of the effects of travoprost, latanoprost and bimatoprost on ocular circulation: a 6‐month clinical trial

Köz

Özsoy

Yarangümeli

et al. 2007

Acta Ophthalmologica Scandinavica

View full text Add to dashboard Cite

show abstract

“…Means are followed by the standard deviation and, in the tables, by the 95% confidence interval (CI). Decimals are omitted in accordance with the recommendations of Stefánsson et al. (2006).…”

Section: Methodsmentioning

confidence: 99%

Significant improvements in near vision, reading speed, central visual field and related quality of life after ranibizumab treatment of wet age‐related macular degeneration

Frennesson

Nilsson

Peebo

et al. 2010

Acta Ophthalmologica

View full text Add to dashboard Cite

ABSTRACT.Purpose: To investigate the effects on near visual acuity, reading speed, central visual field and related quality of life of ranibizumab treatment of wet age-related macular degeneration (AMD). Methods: The study was a prospective, non-comparative consecutive case series, followed for 3 months and investigator-driven. Thirty eyes of 30 patients with wet AMD were included, mean age 75 years (range 69-95 years). In addition to a full ophthalmological examination -including best-corrected visual acuity (BCVA; Early Treatment Diabetic Research Study chart), fundus biomicroscopy, fundus photography, fluorescein angiography, indocyanine green angiography (occult cases) and ocular coherence tomography -near visual acuity, reading speed, central visual field and quality of life for related activities were also investigated at baseline and at 3 months after ranibizumab treatment. Results: Mean BCVA increased from 62 ± 11 to 66 ± 14 letters at 3 months (7%; p = 0.018). Near vision improved from 9 ± 5 to 6 ± 3 points (33%; p = 0.0006) and reading speed increased from 59 ± 40 to 85 ± 50 words ⁄ min (44%; p < 0.0001). The mean deviation from normal of the visual field improved from )9 ± 7 to )6 ± 5 dB (33%; p < 0.0001). Quality of life improved for distance activities from 54 ± 28 to 63 ± 28 points (17%; p < 0.0001) but significantly (p = 0.024) more for near activities, from 49 ± 26 to 63 ± 26 points (29%; p < 0.0001). Reading newspaper text in the group in which the better eye was treated showed the highest increase in quality of life score of all: 116%. Conclusion: The increase in BCVA after ranibizumab treatment is well established.The present study also showed significant improvements in other important visual qualities, such as near visual acuity, reading speed, central visual field and several activities influencing quality of life. The improvement was greater for near activities than for distance activities. Therefore, the beneficial effects of ranibizumab treatment shown here are more extensive than those reported previously.

show abstract

“…The data would be better presented as 77 (SD 19). The latter is not only simpler and clearer but also more correct in that the former implied a degree of precision, which was misleading (Stefánsson et al. 2006).…”

Section: Resultsmentioning

confidence: 99%