Control barrier functions (CBFs) have recently become a powerful method for rendering desired safe sets forward invariant in single-and multi-agent systems. In the multiagent case, prior literature has considered scenarios where all agents cooperate to ensure that the corresponding set remains invariant. However, these works do not consider scenarios where a subset of the agents are behaving adversarially with the intent to violate safety bounds. In addition, prior results on multi-agent CBFs typically assume that control inputs are continuous and do not consider sampled-data dynamics. This paper presents a framework for normally-behaving agents in a multi-agent system with heterogeneous control-affine, sampleddata dynamics to render a safe set forward invariant in the presence of adversarial agents. The proposed approach considers several aspects of practical control systems including input constraints, clock asynchrony and disturbances, and distributed calculation of control inputs. Our approach also considers functions describing safe sets having high relative degree with respect to system dynamics. The efficacy of these results are demonstrated through simulations.