Abstract:Periosteum has shown potential as an effective barrier membrane for
guided bone regeneration (GBR). However, if recognized as a “foreign
body”, insertion of a barrier membrane in GBR treatment will inevitably
alter the local immune microenvironment and subsequently influence bone
regeneration. The aim of this investigation was to fabricate
decellularized periosteum (DP) and investigate its immunomodulatory
properties in GBR. DP was successfully fabricated from periosteum from
the mini-pig cranium. In vitro exp… Show more
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