Decellularization and enzymatic preconditioning of bovine uterus for improved recellularization
Edina Sehic,
Lucía de Miguel-Gómez,
Emy Thorén
et al.
Abstract:Background
Uterus tissue engineering aims to repair a dysfunctional uterus that causes infertility, e.g., after significant scarring from benign or malign resection procedures. Decellularized uterine tissue provided regenerative support in several animal models as a biocompatible natural extracellular matrix (ECM) derived scaffold after uterine damage. However, variations in decellularization protocols and species used limit conclusive evidence and translational progress. Hence, a species-indep… Show more
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