Decarboxylative Allylation of Ketone Enolates with Rh, Ir, and Mo

Abstract

Decarboxylative Allylation of Ketone Enolates with Rh, Ir, and MoA variety of catalysts were investigated for their ability to impart branched regioselectivity in decarboxylative allylation reactions. While catalysts based on Mo, Rh, and Ir were active catalysts, their regio-selectivities were low and the reactions required an equivalent of base for efficient coupling. Alternatively, a ruthenium-based catalyst was identi-fied that operates under neutral conditions and gives high branched selectivity in decarboxylative allylations.