Decalcification of a choroidal osteoma.

Trimble, Susan N.; Schatz, Howard

doi:10.1136/bjo.75.1.61

Cited by 32 publications

(28 citation statements)

References 6 publications

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“…Growth may occur in over 40% of cases if followed for long enough. 169 Conversely, spontaneous decalcification 179,180 or involution 181 of a choroidal osteoma has also been observed.…”

Section: Primary Choroidal Tumoursmentioning

confidence: 99%

Things that go bump in the light. The differential diagnosis of posterior uveal melanomas

Rennie

2002

Eye

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“…Growth may occur in over 40% of cases if followed for long enough. 169 Conversely, spontaneous decalcification 179,180 or involution 181 of a choroidal osteoma has also been observed.…”

Section: Primary Choroidal Tumoursmentioning

confidence: 99%

Things that go bump in the light. The differential diagnosis of posterior uveal melanomas

Rennie

2002

Eye

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“…It is not known whether the photocoagulation was the cause of the complete resolution or whether an increased level of laser-induced osteoclastic activity was the mechanism involved in the decalcification. 9,12 In the case of choroidal osteoma reported by Rose, Burke and Brockhurst, 9 areas of resorption of choroidal osteoma coincided with areas that had received the laser photocoagulation and it was suggested that photocoagulation is capable of ablating bone tissues. In cases where progression of osteoma threatens the macula, such as in the right eye of this patient, a barrier line of laser to the advancing edge of the tumour is indicated.…”

Section: Discussionmentioning

confidence: 99%

“…9,12,23,24 In particular, Trimble and colleagues 12,23 reported two cases of complete decalcification of choroidal osteoma, where both patients had received photocoagulation treatment for subretinal neovascularisation. It is not known whether the photocoagulation was the cause of the complete resolution or whether an increased level of laser-induced osteoclastic activity was the mechanism involved in the decalcification.…”

Section: Discussionmentioning

confidence: 99%

“…The major factor causing visual compromise from choroidal osteoma is the development of choroidal neovascularisation, which is often associated with the formation of subretinal fluid and haemorrhage. 6,8,9,11,12 Aylward and colleagues 6 found that more than one half of the patients had developed choroidal neovascularisation within 20 years of the initial diagnosis of the disease and this was a major cause of subsequent visual loss. Similar to other types of choroidal neovascularisation, the associated occurrence of sub-foveal haemorrhage or disciform scarring leads to a poor visual outcome.…”

mentioning

confidence: 99%

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Choroidal osteoma: evidence of progression and decalcification over 20 years

Chen

Lee

Gass

2006

Clinical and Experimental Optometry

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Choroidal osteoma is a rare, benign, ossifying tumour of the choroid of unknown aetiology. In contrast to other types of intraocular ossification, choroidal osteoma is found typically in young healthy females in the second or third decades of life with no history of systemic or ocular disease. Choroidal osteoma is a deep, pale yellow lesion with distinct geographic borders at the juxtapapillary or macular region, with branching 'spider' vessels on the surface of the tumour. These features should help differentiate choroidal osteoma from other types of intraocular tumour and the diagnosis can be confirmed with ultrasonography and computerised tomography. Here we report an initially unilateral case of choroidal osteoma, which decalcified over 20 years but during the same period the fellow eye also developed a choroidal osteoma to become a bilateral case. Despite the benign nature of the tumour, vision may be compromised by gradual atrophy of the overlying retina, serous retinal detachment, accumulation of sub-retinal fluid and sub-retinal haemorrhage associated with choroidal neovascularisation. Frequent examinations are recommended for patients with choroidal osteoma, for early detection of a subretinal neovascular membrane and potential treatment with laser photocoagulation.

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“…The typical characteristics of choroidal osteomas are their unilaterality, juxta- or peripapillary location, predominance in young females [2], rapid or slow tumor progression [3,4,5], tumor involution [6] and decalcification [7,8]. Diagnosis, by convention, is made by clinical examination and fundus angiography, and confirmed by the presence of choroidal calcification on ultrasonography or other modes of imaging such as computed tomography.…”

Section: Introductionmentioning

confidence: 99%