1958
DOI: 10.1016/s0021-9258(19)77309-8
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Deazapteridines and Deazapurines, Inhibitory Analogues of Folic Acid and Guanine

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1963
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Cited by 13 publications
(6 citation statements)
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“…Anal. (CsoH^NsOs) C, , N. Ethyl 3-[(p-Methoxycarbonyl-lV-methylanilino)methyl]-5(6H)-oxopyrido [3,4-fe]pyrazine-7-carbamate (5). A stirred suspension of finely powdered 4 (100 mg, 0.242 mmol) in H20 (10 ml), EtOH (1 ml), and 1 N NaOH (0.32 ml, 0.32 mmol) was treated dropwise with a 0.27% solution of KMn04 (9.44 ml, 0.161 mmol) in H20.…”
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“…Anal. (CsoH^NsOs) C, , N. Ethyl 3-[(p-Methoxycarbonyl-lV-methylanilino)methyl]-5(6H)-oxopyrido [3,4-fe]pyrazine-7-carbamate (5). A stirred suspension of finely powdered 4 (100 mg, 0.242 mmol) in H20 (10 ml), EtOH (1 ml), and 1 N NaOH (0.32 ml, 0.32 mmol) was treated dropwise with a 0.27% solution of KMn04 (9.44 ml, 0.161 mmol) in H20.…”
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confidence: 99%
“…p-[[(7-Amino-5(6JY)-oxopyrido [3,[4][5][6]pyrazin-3-yl)methyl]methylaminojbenzoic Acid (6). A stirred solution of 5 (2.23 g, 5.43 mmol) and KOH (11.2 g) in EtOH (200 ml) was refluxed under N2 for 16 hr and evaporated to dryness in vacuo.…”
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