Deazaflavin metabolite produced by endosymbiotic bacteria controls fungal host reproduction
Ingrid Richter,
Mahmudul Hasan,
Johannes W Kramer
et al.
Abstract:The endosymbiosis between the pathogenic fungus Rhizopus microsporus and the toxin-producing bacterium Mycetohabitans rhizoxinica represents a unique example of host control by an endosymbiont. Fungal sporulation strictly depends on the presence of endosymbionts as well as bacterially produced secondary metabolites. However, an influence of primary metabolites on host control remained unexplored. Recently, we discovered that M. rhizoxinica produces FO and 3PG-F420, a derivative of the specialized redox cofacto… Show more
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