Deaths From Methylene Chloride Exposure

Rosenman, Kenneth D.

doi:10.1001/jamainternmed.2021.1058

Cited by 2 publications

(2 citation statements)

References 2 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Long-term exposure has been associated with a lot of deleterious systemic disruptions 30 . The biochemical basis of the ferocious effect of methylene chloride was linked to its major metabolic pathways which involve the hepatic oxidation via cytochrome P450 2E1 (CYP2E1) and conjugation via Glutathione-S-Transferase Theta 1 (GSTT1) 31,32 . Spontaneous abortion is associated with the methylene chloride pathway stated above.…”

Section: Resultsmentioning

confidence: 99%

See 1 more Smart Citation

Chemistries of Monkey Tail Drink Commonly Patronized in Otuoke, Bayelsa State, Nigeria

Agoro¹,

Thomas²

2023

American J. of Food Technology

View full text Add to dashboard Cite

Background and Objective: Monkey tail is a sieved mixture of alcohol (Ogogoro) and marijuana (Cannabis sativa). It is prepared by brewing the leaves, roots, stem, or seeds of marijuana in Ogogoro for a few days or more. Monkey tail is heavily patronized for euphoric, medicinal and intoxicating purposes without empirical data. The study was designed to identify the chemical composition of monkey tail to over whether it is toxic, therapeutic, or mixed. Materials and Methods: Ten samples of monkey tail bought from ten different vendors were analyzed for heavy metals and other bioactive compounds using Atomic Absorption Spectrophotometry (AAS) and gas chromatography (GC), respectively. Results: The findings revealed an increase in mean concentrations of cadmium and lead, whereas chromium concentration is decreased in monkey tail when compared to WHO permissible limits. In a similar vein, eighteen bioactive ingredients with varying concentrations were also observed in a chromatogram. Three of the eighteen compounds observed constituted about 60%. They include dichloroacetic which constitutes 27.536%, methylene chloride 16.285% and derivative of trimethyl 14.081%. Conclusion: Some of the compounds discovered are therapeutic, whereas others were toxic. In conclusion, monkey tail could be described as a mixture that is either toxic or therapeutic.

show abstract

Section: Resultsmentioning

confidence: 99%

“…Spontaneous abortion is associated with the methylene chloride pathway stated above. A Finnish case study involving possible causes of spontaneous abortions among 44 women working in the pharmaceutical industry showed an increased risk associated with exposure to several chemicals and solvents inclusive of methylene chloride 32 .…”

Section: Resultsmentioning

confidence: 99%