Death in geriatric pneumonia patients

Ikeda, Nobuhiro; Aiba, Miyoji; Sakurai, Takako; Takahashi, Miki; Yang, Kwang Seok; Tsuda, Hiroshi; Isonuma, Hiroshi

doi:10.3143/geriatrics.48.282

Cited by 3 publications

(6 citation statements)

References 7 publications

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“…Oral and dental cleansing reduces morbidity and mortality in this group 42 . Pneumonia is a life‐threatening disease that should be treated aggressively 41,42 . Patients who are debilitated can readily succumb to pneumonia.…”

Section: Clinical Significancementioning

confidence: 99%

“…For people over age 65, pneumonia is the fourth leading cause of death. 41 People with dementia and/or cerebrovascular disease are likely dysphagic, and thus at risk for aspiration pneumonia. 41 These individuals may be trained to swallow in such a way that can reduce the incidence of aspiration pneumonia.…”

Section: Aspiration Pneumoniamentioning

confidence: 99%

“…41 People with dementia and/or cerebrovascular disease are likely dysphagic, and thus at risk for aspiration pneumonia. 41 These individuals may be trained to swallow in such a way that can reduce the incidence of aspiration pneumonia. 41 However, studies 42,43 have shown that oral cleaning and scaling of the teeth can dramatically reduce the occurrence of aspiration pneumonia in people who are elderly.…”

Section: Aspiration Pneumoniamentioning

confidence: 99%

“…41 These individuals may be trained to swallow in such a way that can reduce the incidence of aspiration pneumonia. 41 However, studies 42,43 have shown that oral cleaning and scaling of the teeth can dramatically reduce the occurrence of aspiration pneumonia in people who are elderly. Oral and dental cleansing reduces morbidity and mortality in this group.…”

Section: Aspiration Pneumoniamentioning

confidence: 99%

“…42 Pneumonia is a life-threatening disease that should be treated aggressively. 41,42 Patients who are debilitated can readily succumb to pneumonia. Oral pathogens are capable of migrating through the pharynx through the bronchi and into the alveoli, then colonizing respiratory structures, potentially resulting in the death of the patient.…”

Section: Aspiration Pneumoniamentioning

confidence: 99%

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Inspissated oral secretions and a review of their clinical, biological, and physiological significance

Flanagan

2012

Special Care in Dentistry

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People with some chronic diseases may dehydrate and develop thick, viscous inspissated oronasal secretions that include cellular debris. This material can lead to ductal or airway obstructions that can prove to be life threatening. Asthma, allergy with superinfection, cystic fibrosis, intubated ventilation, burn injuries, and medication-induced complications are discussed in this paper. Many patients with chronic debilitating conditions may also be unable to communicate, and so may be unable to verbally convey that they have a compromised airway or an obstruction. Therefore, it is essential to maintain hydration and good oral hygiene that not only addresses the teeth and prostheses, but also the oral mucosal surfaces. People who are institutionalized and bed-ridden, in particular, need to be closely monitored to prevent adverse sequellae. A daily oral sweep with a 4 × 4 surgical sponge moistened with chlorhexidine may prevent aspiration pneumonia or a fatality due to an airway obstruction. Human oronasal secretions are involved with immunity, digestion, lubrication, and speech. Saliva is the most volumetrically important. These secretions moisturize inspired and expired air but can lose water, causing an increase in viscosity. The viscous secretions trap particles, food debris, and bacterial colonies, thereby increasing inspissations that may obstruct the airway.

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Section: Clinical Significancementioning

confidence: 99%

Section: Aspiration Pneumoniamentioning

confidence: 99%

Section: Aspiration Pneumoniamentioning

confidence: 99%

Section: Aspiration Pneumoniamentioning

confidence: 99%

Section: Aspiration Pneumoniamentioning

confidence: 99%

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Inspissated oral secretions and a review of their clinical, biological, and physiological significance

Flanagan

2012

Special Care in Dentistry

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Knockdown CRNDE alleviates LPS-induced inflammation injury via FOXM1 in WI-38 cells

Zhuge

Yang

Jiang

2018

Biomedicine & Pharmacotherapy

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The risk factors and predictive modeling of mortality in patients with mental disorders combined with severe pneumonia

Li,

Zhou,

Wang

et al. 2024

Front. Psychiatry

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BackgroundWe explored clinical characteristics and risk factors for mortality in patients with mental disorders combined with severe pneumonia and developed predictive models.MethodsWe retrospectively analyzed the data of 161 patients with mental disorders combined with severe pneumonia in the intensive care unit (ICU) of a psychiatric hospital from May 2020 to February 2023, and divided them into two groups according to whether they died or not, and analyzed their basic characteristics, laboratory results and treatments, etc. We analyzed the risk factors of patients' deaths using logistics regression, established a prediction model, and drew a dynamic nomogram based on the results of the regression analysis. Based on the results of regression analysis, a prediction model was established and a dynamic nomogram was drawn.ResultsThe non-survivor group and the survivor group of patients with mental disorders combined with severe pneumonia were statistically different in terms of age, type of primary mental illness, whether or not they were intubated, whether or not they had been bedridden for a long period in the past, and the Montreal Cognitive Assessment (MoCA) scale, procalcitonin (PCT), albumin (ALB), hemoglobin (Hb), etc. Logistics regression analysis revealed the following: MoCA scale (OR = 0.932, 95% CI:0.872–0.997), age (OR = 1.077, 95%CI:1.029–1.128), PCT (OR = 1.078, 95% CI:10.006–10.155), ALB (OR = 0.971, 95%CI:0.893–1.056), Hb (OR = 0.971, 95% CI: 0.942–0.986) were statistically significant. The ROC curve showed that the model predicted patient death with an area under the curve (AUC) of 0.827 with a sensitivity of 73.4% and a specificity of 80.4%.ConclusionLow MoCA score, age, PCT, and low Hb are independent risk factors for death in patients with mental disorders with severe pneumonia, and the prediction model constructed using these factors showed good predictive efficacy.

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Death in geriatric pneumonia patients

Cited by 3 publications

References 7 publications

Inspissated oral secretions and a review of their clinical, biological, and physiological significance

Inspissated oral secretions and a review of their clinical, biological, and physiological significance

Knockdown CRNDE alleviates LPS-induced inflammation injury via FOXM1 in WI-38 cells

The risk factors and predictive modeling of mortality in patients with mental disorders combined with severe pneumonia

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