Abstract:Osteoporosis is a prevalent disease with several current treatments. However, these treatments can have harmful long‐term side effects on individuals utilizing them. Reveromycin A (Rev A) is a natural compound that specifically causes apoptosis in osteoclasts but not osteoblasts. To further test whether Rev A can be a safe osteoporosis treatment without detrimental effects in the surrounding joint, the compound’s ability to induce apoptosis and necrosis in ATDC5 murine chondrocytes and HIG‐82 rabbit synoviocyt… Show more
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