2001
DOI: 10.1016/s1053-2498(00)00228-x
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Death after rejection with severe hemodynamic compromise in pediatric heart transplant recipients: a multi-institutional study

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Cited by 97 publications
(72 citation statements)
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“…Based on several studies from the PHTS, recipients with the following characteristics most likely fall into this group: any history of ER (initial, recurrent or with hemodynamic compromise); non-white race; older age at transplant (any recipient Ͼ1 year of age at time of transplant); those without history of congenital heart disease; and those with a male donor. 2,4,12,13 Further analyses are needed to evaluate additional risk factors for development of coronary vasculopathy, but improvement in incidence of LR should also portend less risk of vasculopathy or need for retransplantation.…”
Section: Discussionmentioning
confidence: 99%
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“…Based on several studies from the PHTS, recipients with the following characteristics most likely fall into this group: any history of ER (initial, recurrent or with hemodynamic compromise); non-white race; older age at transplant (any recipient Ͼ1 year of age at time of transplant); those without history of congenital heart disease; and those with a male donor. 2,4,12,13 Further analyses are needed to evaluate additional risk factors for development of coronary vasculopathy, but improvement in incidence of LR should also portend less risk of vasculopathy or need for retransplantation.…”
Section: Discussionmentioning
confidence: 99%
“…Structure of the PHTS and data collection methods and have been described previously. [13][14][15] The data included all transplants performed between January 1993 and December 2007. Data were analyzed to assess for era-effect in 2 eras: (1) early era included HTxs performed between 1993 and 1998; and (2) current era included HTxs performed between 1999 and 2007.…”
Section: Patient Populationmentioning
confidence: 99%
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“…The study demonstrates that black paediatric heart transplant recipients had a significantly lower graft survival rate compared with other racial groups, 51% versus 69%. There have been several other reports that demonstrate a higher graft rejection after paediatric heart transplant among black recipients (Chin et al, 2004;Pahl et al, 2001). In comparison, research conducted in a cardiac transplant center in the United Kingdom (UK) included 78 children who underwent a heart transplant between 2001 and 2005.…”
Section: Social Outcomesmentioning
confidence: 99%
“…1,2 The first year after transplant remains the time of greatest risk, with decreasing incidence in later years. [1][2][3][4] Age at transplant plays a role as well, with the lowest risk reported in infant recipients, whereas older recipients carry a higher risk of rejection. 1,2,5 Diagnosing rejection can be relatively straightforward in a symptomatic patient.…”
mentioning
confidence: 99%