Deactivation in the posterior mid-cingulate cortex reflects perceptual transitions during binocular rivalry: Evidence from simultaneous EEG-fMRI

Roy, Abhrajeet V.; Jamison, Keith; He, Sheng; Engel, Stephen A.; He, Bin

doi:10.1016/j.neuroimage.2017.02.041

Cited by 27 publications

(35 citation statements)

References 40 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…locus coeruleus 61 which is the source of noradrenaline in the forebrain 62 and is involved in attention, or raphe nuclei, responsible for the release of serotonin 63 , whose levels have been shown to affect rivalry alternations 64 ) that projects to these frontal structures. While medial frontal activation has been reported in a few fMRI studies of bistable perception 15 , 20 , 21 , 23 , 24 , most of these studies found activations in lateral prefrontal regions. The region that is most consistently implicated in imaging studies (also after controlling for the matched duration 16 and no-report criticism 19 , 65 , 66 ) is the inferior frontal cortex (IFC).…”

Section: Discussionmentioning

confidence: 95%

“…These neurons did not show selective responses during the non-rivalrous condition. Inspired by fMRI reports of frontal involvement in perceptual transitions 15 , 16 , 21 , 23 , 24 , 40 – 42 (but see ref. 43 ) we looked for units that changed their FR compared to baseline around the perceptual transitions, irrespective of image identity.…”

Section: Resultsmentioning

confidence: 99%

“…Similarly, as opposed to previous monkey single unit studies of subjective perception that targeted lateral frontal areas 45 – 48 , this study focused on neurons in medial frontal areas (specifically the preSMA and ACC). Second, the high spatiotemporal resolution of single unit recordings allowed us to extend previous fMRI BR studies 15 , 21 , 49 , 50 in closely tracking the time-courses of MTL vs. frontal activity during rivalry and replay. These comparisons showed that ACC/preSMA activity precedes MTL activity.…”

Section: Discussionmentioning

confidence: 97%

See 2 more Smart Citations

Human single neuron activity precedes emergence of conscious perception

et al. 2018

View full text Add to dashboard Cite

Identifying the neuronal basis of spontaneous changes in conscious experience in the absence of changes in the external environment is a major challenge. Binocular rivalry, in which two stationary monocular images lead to continuously changing perception, provides a unique opportunity to address this issue. We studied the activity of human single neurons in the medial temporal and frontal lobes while patients were engaged in binocular rivalry. Here we report that internal changes in the content of perception are signaled by very early (~-2000 ms) nonselective medial frontal activity, followed by selective activity of medial temporal lobe neurons that precedes the perceptual change by ~1000 ms. Such early activations are not found for externally driven perceptual changes. These results suggest that a medial fronto-temporal network may be involved in the preconscious internal generation of perceptual transitions.

show abstract

Section: Discussionmentioning

confidence: 95%

Section: Resultsmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 97%

See 1 more Smart Citation

Human single neuron activity precedes emergence of conscious perception

et al. 2018

View full text Add to dashboard Cite

show abstract

“…During binocular rivalry, dissimilar monocular images presented to each eye compete for perceptual dominance, with conscious awareness typically fluctuating spontaneously between each image (Alais, 2012;Alais & Blake, 2005;Levelt, 1965;Maier, Panagiotaropoulos, Tsuchiya, & Keliris, 2012). When two flickering stimuli compete during rivalry, the relative strength of frequency-tagged activity positively correlates with behavioural reports of the dominant image (Bock, Fesi, Baillet, & Mendola, 2019;Brown & Norcia, 1997;Cosmelli et al, 2004;Jamison, Roy, He, Engel, & He, 2015;Kamphuisen, Bauer, & van Ee, 2008;Katyal et al, 2016;Lansing, 1964;Lawwill & Biersdorf, 1968;Roy, Jamison, He, Engel, & He, 2017;Srinivasan, Russell, Edelman, & Tononi, 1999;Sutoyo & Srinivasan, 2009;Tononi et al, 1998;Zhang et al, 2011) .…”

Section: Introductionmentioning

confidence: 99%

The SSVEP tracks attention, not consciousness, during perceptual filling-in

Davidson

Mithen

Hogendoorn

et al. 2020

eLife

View full text Add to dashboard Cite

Research on the neural basis of conscious perception has almost exclusively shown that becoming aware of a stimulus leads to increased neural responses. By designing a novel form of perceptual filling-in (PFI) overlaid with a dynamic texture display, we frequency-tagged multiple disappearing targets as well as their surroundings. We show that in a PFI paradigm, the disappearance of a stimulus and subjective invisibility is associated with increases in neural activity, as measured with steady-state visually evoked potentials (SSVEPs), in electroencephalography (EEG). We also find that this increase correlates with alpha-band activity, a well-established neural measure of attention. These findings cast doubt on the direct relationship previously reported between the strength of neural activity and conscious perception, at least when measured with current tools, such as the SSVEP. Instead, we conclude that SSVEP strength more closely measures changes in attention.

show abstract

“…Furthermore, when stimuli are flickered to generate a steady-state visual evoked potential (SSVEP), the signatures of competition can be found in the occipital and middle temporal (hMT/V5) visual areas (Zhang, Jamison, Engel, He, & He, 2011 ). Investigations of concurrent SSVEP and fMRI studies suggest involvement of other brain areas in parietal and cingulate regions alongside early visual areas (Roy, Jamison, He, Engel, & He, 2017 ). Thus, early visual areas show competitive interactions with coordinated activity occurring throughout the visual system as a consequence of resolving rivalry.…”

Section: Introductionmentioning

confidence: 99%

Stimulus rivalry and binocular rivalry share a common neural substrate

Petruk

Engel

et al. 2018

Journal of Vision

Self Cite

View full text Add to dashboard Cite

When two incompatible images are shown separately to each eye, a perceptual process known as binocular rivalry occurs by which the two images compete for awareness. The site of competition for binocular rivalry has been a topic of debate, and recent theories are that it may occur either at low levels of the visual system where the inputs from the two eyes are combined or at high levels of the visual system where the two images are processed. One of the major pieces of evidence for a high-level image account of rivalry is a phenomenon known as stimulus rivalry, in which two competing stimuli are swapped between the eyes at 3 Hz. However, there is little available neurophysiological evidence for a neural substrate for this high-level competition. Here, we used frequency tagging of two competing stimuli in binocular rivalry and stimulus rivalry in humans to evaluate whether the steady-state visually evoked potentials (SSVEPs) show similar signatures of neural competition for both conditions. We found that flickering the stimuli generates spectral power at the tagged frequencies in both types of rivalry in the early visual cortex. We then quantified dynamic signatures of competition by tracking amplitude changes in the frequency tags, which showed that both types of rivalry colocalized in occipital regions of the cortex. Thus, contrary to our hypothesis that stimulus rivalry was being mediated by high-level competition between the images, we find that neural competition measured by the SSVEP instead suggests that the sites of competition for stimulus rivalry and binocular rivalry may similarly include the occipital pole and middle temporal gyrus (hMT+/V5) of the visual system, consistent with a low-level, binocular interpretation.

show abstract

Deactivation in the posterior mid-cingulate cortex reflects perceptual transitions during binocular rivalry: Evidence from simultaneous EEG-fMRI

Cited by 27 publications

References 40 publications

Human single neuron activity precedes emergence of conscious perception

Human single neuron activity precedes emergence of conscious perception

The SSVEP tracks attention, not consciousness, during perceptual filling-in

Stimulus rivalry and binocular rivalry share a common neural substrate

Contact Info

Product

Resources

About