De novo malignant eccrine spiradenoma and metachronous lung cancer

Abstract

Malignant eccrine spiradenoma is an extremely rare sweat-gland tumour. Herein we aimed to present an 81-yearold woman with malignant eccrine spiradenoma repeated on the thigh and metachronous lung cancer. She presented with a palpable swelling in the right thigh region. Her systemic screening was normal and excisional biopsy was performed. A diagnosis of malignant eccrine spiradenoma was made. Thirty-two months later, the tumour recurred in the same region. The tumour was excised again. Lymph node metastasis was also detected in lymph node dissection. Fifteen months later, the tumour recurred again in the same place. In addition, lymph node metastasis and bone metastasis were found. Palliative radiotherapy was performed for the involvement of the right femur. The treatment for metachronous lung cancer could not be given because of the patient's age and performance, and she could not be given additional treatment for the same reasons.

Challenges in diagnosis and management of a spiradenocarcinoma: a comprehensive literature review

“…25,87 All of the cases with margins of <1 cm, on the other hand, reported distant metastases, while two patients died. 1,38,77,79,86 The mean time to local recurrence or metastasis after initial therapy was 20.1 months (range 0-192 months). Approximately, 75% of these were detected in the first 12 months of follow up.…”

“…Computed tomography was the preferred modality, used in 49.1% of these cases, followed by magnetic resonance imaging (MRI) (32.7%), X-ray (30.9%), bone scan (23.6%), ultrasound (20%), positron emission tomography (PET)/computed tomography (CT) (14.5%) and finally mammography (10.9%). [4][5][6][8][9][10][11][54][55][56][57][58][60][61][62][63][67][68][69][73][74][75][77][78][79] Staiger et al have recently recommended that patients presenting with confirmed malignant spiradenoma be evaluated with an MRI and fluorodeoxyglucose (FDG)-PET/CT. 74 Details regarding a fineneedle aspirate or punch biopsy was provided for 76 case reports and case series, representing 86 (61.9%) cases.…”

“…This pre-operative test was performed 40.7% of the time, with the majority of surgeons electing to proceed firstly with excisional biopsy or wide local excision. [4][5][6][7][8][9][10][11][12][18][19][20][21][22][24][25][26][27][28][29][54][55][56][57][58][60][61][62][63][64][65][66][67][68][69][70][71][72][73][74][75][77][78][79][80][81][82][83][84][85][86][8...…”