De Novo Crohn's Disease Triggered After COVID-19: Is COVID-19 More Than an Infectious Disease?

Abstract

Coronavirus disease 2019 (COVID-19)-associated immune dysregulation is believed to trigger the onset of various autoimmune diseases. These occur either during active COVID-19 or soon after recovery. We report ileocolonic Crohn's disease in a 35-year-old woman after her recovery from a milder form of COVID-19. She achieved remission of her symptoms with oral corticosteroids and sulfasalazine.

Hemophagocytic Lymphohistiocytosis in A Post Covid-19 Patient with Mds: A Case Report

“…Moreover the virus binds to the angiotensin-converting enzyme 2 (ACE-2) receptors and leads to activation and redistribution of immune cells [32][33][34][35]. There have been many references in the literature regarding the development of autoimmune diseases including granulomatous diseases as well as bone marrow involvement in patients following COVID-19 [36][37][38][39][40][41][42].…”

Chronisch-entzündliche Darmerkrankungen in der COVID-Pandemie: Manifestationen und Management

“…Und so gibt es durchaus Patient*innen, die über deutliche CED-Schub-typische Beschwerden berichten und dieses auch über soziale Medien teilen. Ebenso wurde auch in der wissenschaftlichen Literatur von Einzelfällen einer postvakzinalen Erstmanifestation eines M. Crohn berichtet [42]. Vor diesem Hintergrund sind valide epidemiologische Untersuchungen wichtig.…”

SARS-CoV-2 infection as a potential trigger factor for de novo occurrence of inflammatory bowel disease

“…Since we know that acute viral gastroenteritis can trigger the onset of IBD [2], a literature search was conducted in PubMed, using the words [ Six cases of new-onset IBD, occurring after COVID-19 infection, were identified. There were four UC [3][4][5][6] cases and two CD [7,8] cases (Table 1). IBD following COVID-19 mainly occurred in women (four out of six).…”

“…Six cases of new-onset IBD, occurring after COVID-19 infection, were identified. There were four UC [3–6] cases and two CD [7,8] cases (Table 1). IBD following COVID-19 mainly occurred in women (four out of six).…”