De novo biosynthesis of linoleic acid in insects

Cripps, Colleen; Blomquist, Gary J.; Renobales, Mertxe de

doi:10.1016/0005-2760(86)90046-9

Cited by 85 publications

(67 citation statements)

References 17 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Basically, almost all herbivores and omnivores have a dietary requirement for two essential fatty acids that cannot be synthesized de novo, i.e., linoleic and linolenic acid (C18:206 and C18:303, respectively). However, some invertebrates have been found that are capable of synthesizing linoleic acid (Cripps et al 1982) and, as a consequence, are not completely dependent on intake of linoleic acid with their diet (Stanley-Samuelson et al 1988). Linoleic and linolenic fatty acids are precursors for long-chained PUFAs such as arachidonic acid (C20:4ij6) and eicosapentaenoic acid (EPA, C20:503).…”

Section: Discussionmentioning

confidence: 99%

Growth and reproduction of Daphnia galeata in response to changes in fatty acids, phosphorus, and nitrogen in Chlamydomonas reinhardtii

Weers

Gulati

1997

Limnology & Oceanography

110

105

View full text Add to dashboard Cite

The importance of changes in elemental and fatty acid composition of the algal food for Daphnia galeata was investigated. The green alga Chlamydomonas reinhardtii was grown under nitrogen or phosphorus limitation to modify its elemental and biochemical composition. Both N-and P-limited slgae exhibited similar fatty acid compositions but differed from algae grown under N and P saturation. Nutrient iimitation of algae caused the amounts of saturated fatty acids, monounsaturated, and diunsaturated fatty acids to ncrease, but those of polyunsaturated fatty acids to decrease markedly. Life-history experiments with D. galeatu, carried out to examine the effects of the varying N and P regimes to the food quality of Chlamydomonas, revealed that N-limited and N+P-saturated algae were of a comparable quality. In contrast, P-limited alga was a very poor food; that is, both population growth and somatic growth rate were much lower than with N-and N+P-saturated algae. Differences of algal fatty acid composition did not explain the differences in algal food quality as N+P-saturated and N-limited Chlamydomonas were both similar in quality despite differences in fatty acid composition. P limitation of daphnid growth is more consistent with the observed differences in growth and reproduction. The low growth rates of the daphnids when fed P-limited alga, however, may also be a result of indirect effects because P limitation may induct changes in algal morphology or biochemical compounds other than fatty acids.

show abstract

Section: Discussionmentioning

confidence: 99%

Growth and reproduction of Daphnia galeata in response to changes in fatty acids, phosphorus, and nitrogen in Chlamydomonas reinhardtii

Weers

Gulati

1997

Limnology & Oceanography

110

105

View full text Add to dashboard Cite

show abstract

“…Consensus between phylogenies based on morphology and molecular data has not yet been reached satisfyingly, and relationships among hymenopteran superfamilies are thus regarded as polytomous in this study. Within Hymenoptera, data on lipogenic ability have been obtained for parasitoids of the superfamilies Proctotrupoidea, Cynipoidea and Chalcidoidea (Proctotrupomorpha), and Ichneumonoidea and Chrysidoidea (Aculeata) (22,56,57). As the analysis does not allow polytomies, three alternative consensus trees were used for phylogenetic testing within Hymenoptera.…”

Section: Methodsmentioning

confidence: 99%

Loss of lipid synthesis as an evolutionary consequence of a parasitic lifestyle

Visser¹,

Lann

Blanken³

et al. 2010

Proc. Natl. Acad. Sci. U.S.A.

170

237

View full text Add to dashboard Cite

International audienceEvolutionary loss of traits can result from negative selection on a specific phenotype, or if the trait is selectively neutral, because the phenotype associated with the trait has become redundant. Even essential traits may be lost, however, if the resulting phenotypic deficiencies can be compensated for by the environment or a symbiotic partner. Here we demonstrate that loss of an essential metabolic trait in parasitic wasps has evolved through environmental compensation. We tested 24 species for the ability to synthesize lipids de novo and collected additional data from the literature. We found the majority of adult parasitoid species to be incapable of synthesizing lipids, and phylogenetic analyses showed that the evolution of lack of lipogenesis is concurrent with that of parasitism in insects. Exploitive host manipulation, in which the host is forced to synthesize lipids to the benefit of the parasitoid, presumably facilitates loss of lipogenesis through environmental compensation. Lipogenesis re-evolved in a small number of parasitoid species, particularly host generalists. The wide range of host species inwhich generalists are able to develop may impede effective host manipulation and could have resulted in regaining of lipogenic ability in generalist parasitoids. As trait loss through environmental compensation is unnoticed at the phenotypic level, it may be more common than currently anticipated, especially in species involved in intricate symbiotic relationships with other species

show abstract

“…These essential fatty acids (FAs) are transferred from leaves, seeds, or phytoplankton to higher trophic levels through the food chain (Budge, Iverson, & Koopman, 2006). A few insect species are exceptions as they produce delta12-desaturase and can convert oleic acid into LA (Brandstetter & Ruther, 2016;Cripps, Blomquist, & de Renobales, 1986;Zhou et al, 2008).…”

Section: Introductionmentioning

confidence: 99%

“…Indeed, the supplementation in dietary ω-3 appears to reduce the risk of coronary heart disease (Bucher, Hengstler, Schindler, & Meier, 2002;Harper & Jacobson, In this study, we aimed to induce a change in the lipid composition of mealworm (Tenebrio molitor) larvae, whose mass is made up of approximately 40% fat (Rumpold & Schlüter, 2013a). This coleopteran species has already been reared for captive insectivorous species and human consumption, and is not known to produce delta12-desaturase (Cripps et al, 1986). We therefore investigated experimentally the effects of diets varying in ω-3/ω-6 ratio and FA concentration but similar in PUFA proportion on the total larva fatty acid (FA) composition.…”

Section: Introductionmentioning

confidence: 99%

Diet Induced Modifications of Fatty-Acid Composition in Mealworm Larvae (Tenebrio molitor)

Fasel

Mène-Saffrané

Ruczyński

et al. 2017

JFR

View full text Add to dashboard Cite

The diet of Western human societies is characterized by an excess of saturated fatty acids (FAs) and a high concentration of ω-6 relative to ω-3 polyunsaturated FA (PUFA). These unbalanced diets are suspected to trigger diseases and disorders. To alleviate this public health concern, the production of healthier meat with more PUFAs of higher ω-3 concentration could potentially be achieved by modifying livestock diets. The high nutritional value and limited breeding costs of edible insects have brought insect feed into the discussion as a promising fat source for animal and human diets. In this study, we sought to increase the amount of ω-3 PUFAs in mealworm (Tenebrio molitor) larvae. We investigated the effects of diets varying in ω-3/ω-6 ratio and FA concentration but similar in PUFA proportion on larva FA composition. Mealworm larvae showed significant plasticity in lipid composition. High dietary ω-3/ω-6 ratios induced an increase in the proportion of ω-3 and a decrease in ω-6, which resulted in higher larval ω-3/ω-6 ratios, but also in higher larval PUFA proportion. Increasing FA concentrations in larva diets also favored the accumulation of PUFAs to the detriment of monounsaturated and saturated FAs. Providing ω-3-rich seeds to mealworm larvae could allow the production of economical animal fat with healthier PUFA percentages (> 60%) and ω-3/ω-6 ratios (>0.5).

show abstract

De novo biosynthesis of linoleic acid in insects

Cited by 85 publications

References 17 publications

Growth and reproduction of Daphnia galeata in response to changes in fatty acids, phosphorus, and nitrogen in Chlamydomonas reinhardtii

Growth and reproduction of Daphnia galeata in response to changes in fatty acids, phosphorus, and nitrogen in Chlamydomonas reinhardtii

Loss of lipid synthesis as an evolutionary consequence of a parasitic lifestyle

Diet Induced Modifications of Fatty-Acid Composition in Mealworm Larvae (Tenebrio molitor)

Contact Info

Product

Resources

About