Abstract:Gastroesophageal reflux disease (GERD) and Barrett's esophagus (BE) continue to be major topics in the field of clinical research. More data are accumulating on the endoscopic diagnosis of subtle abnormalities, to allow better classification of patients into endoscopy-positive and endoscopy-negative (NERD, non-erosive reflux disease) groups. The situation regarding endoscopic antireflux techniques has not become much clearer. Some abstracts were presented to both societies.
Diagnosis of Reflux and EsophagitisV… Show more
Introduction: Glycogenic acanthosis (GA) is a benign, polypoid lesion frequently seen in upper endoscopy with little known aetiology. Information about how it occurs and its clinical significance is lacking. Aim: In this study, the relationship between GA and reflux symptoms was investigated in patients who underwent endoscopy due to reflux symptoms. Material and methods: Sixty patients undergoing endoscopy for reflux symptoms and 60 controls without reflux symptoms were included in the study. Among the patients with reflux symptoms, two groups were formed: GA group 1 (n = 30) and non-GA group 2 (n = 30). Results: The mean age of all patients participating in the study was 44.65 ±15.54 years; in group 1 it was 52.56 ±10.90 years and in group 2 it was 39.40 ±13.87 years. The mean age of group 1 patients was statistically significantly higher than that of group 2 patients (p < 0.05). The incidence of GA was higher in group 1 than in the control group (p = 0.001). In the reflux group, group 1 and group 2 were compared in terms of oesophagitis; group 1 had a higher incidence of oesophagitis (p < 0.05). In the reflux group, in those with GA, the risk of oesophagitis was 6.6 times higher than among those without GA (OR = 6.571; 95% CI: 2.109-20.479). Conclusions: We think that GA is associated with advanced age, reflux disease, and oesophagitis in our study.
Introduction: Glycogenic acanthosis (GA) is a benign, polypoid lesion frequently seen in upper endoscopy with little known aetiology. Information about how it occurs and its clinical significance is lacking. Aim: In this study, the relationship between GA and reflux symptoms was investigated in patients who underwent endoscopy due to reflux symptoms. Material and methods: Sixty patients undergoing endoscopy for reflux symptoms and 60 controls without reflux symptoms were included in the study. Among the patients with reflux symptoms, two groups were formed: GA group 1 (n = 30) and non-GA group 2 (n = 30). Results: The mean age of all patients participating in the study was 44.65 ±15.54 years; in group 1 it was 52.56 ±10.90 years and in group 2 it was 39.40 ±13.87 years. The mean age of group 1 patients was statistically significantly higher than that of group 2 patients (p < 0.05). The incidence of GA was higher in group 1 than in the control group (p = 0.001). In the reflux group, group 1 and group 2 were compared in terms of oesophagitis; group 1 had a higher incidence of oesophagitis (p < 0.05). In the reflux group, in those with GA, the risk of oesophagitis was 6.6 times higher than among those without GA (OR = 6.571; 95% CI: 2.109-20.479). Conclusions: We think that GA is associated with advanced age, reflux disease, and oesophagitis in our study.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.