Day light photodynamic therapy with BF-200 ALA: A case series

Ruiz‐Villaverde, Ricardo; Sáenz‐Guirado, Soledad; Cuenca‐Barrales, Carlos; Aguayo-Carreras, Paula

doi:10.1111/dth.12666

Cited by 1 publication

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References 12 publications

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“…Treatment tolerance has been enhanced by the incorporation of new PDT modalities. Treatment using daylight stands out, 8 and the initial combination of daylight followed by conventional light has subsequently been published, 9 significantly reducing pain and itching during treatment, if compared with treatment of PDT with conventional light. These studies have been published for the treatment of actinic keratosis.…”

Section: Discussionmentioning

confidence: 99%

Treatment of superficial basal cell carcinoma with 7.8% 5‐aminolaevulinic acid nanoemulsion‐based gel ( BF ‐200 ALA ) and photodynamic therapy: Results in clinical practice in a tertiary hospital

Navarro‐Triviño

Ayén‐Rodríguez

Llamas‐Molina

et al. 2020

Dermatologic Therapy

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Photodynamic therapy (PDT) is an effective treatment option for the treatment of superficial basal cell carcinoma (sBCC). Recent publications have demonstrated that PDT with 7.8% 5‐aminolaevulinic acid nanoemulsion‐based gel (BF‐200 ALA‐PDT) is an effective and safe alternative for the treatment of sBCC). To investigate the efficacy and safety of 7.8% 5‐aminolaevulinic acid nanoemulsion‐based gel (BF‐200 ALA)‐PDT for the treatment of sBCC. A non‐controlled, open‐label single centre study was conducted. Patients received one PDT cycle with two PDT sessions one‐week apart. In case that clinical‐dermoscopy evaluation of treatment outcome revealed remaining lesions, a second PDT cycle was performed. The clinical results at the dermoscopy and fluorescence diagnosis level were histologically confirmed in all patients. Treatment response was evaluated 3, 6, and 12 months after last PDT session. A total of 31 patients (12 men and 19 women), with a median age of 63.74 years were included in this study. 3‐month after PDT‐session, 23/31 patients were complete responders (74.19%) after two BF‐200 ALA ‐PDT sessions. Esthetic outcome was considered good‐to‐excellent. 5 Aminolevulinic acid 7.8% nanoemulsion‐based gel (BF‐200 ALA) PDT is an effective therapy option for the treatment of sBCC. Complete clearance rates were higher in those patients who received only one PDT cycle. These results show a similar tendency as shown in other publications.

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Section: Discussionmentioning

confidence: 99%