Day-case minimally invasive excision of a giant mediastinal parathyroid adenoma

Haldar, Anil; Thapar, Ankur; Khan, Shahab; Jenkins, Stephanie

doi:10.1308/003588414x13946184900480

Cited by 13 publications

(16 citation statements)

References 3 publications

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“…Surgical excision of the hyper functioning gland is the treatment of choice for parathyroid adenomas. [ 13 ] The surgical approach for an inferior giant parathyroid adenomas extending on to the mediastinum can be cumbersome requiring a full collar incision or occasionally a median sternotomy. Our case further demonstrates that a focused trans-cervical excision of giant inferior parathyroid adenoma is a viable approach for resection and should be considered prior to a formal neck exploration or sternotomy.…”

Section: Discussionmentioning

confidence: 99%

A rare case of giant parathyroid adenoma presenting with recurrent episodes of pancreatitis

Raghunandan

Ramshankar

2016

Indian J Nucl Med

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Parathyroid adenomas are usually small in size; (weighing 70 mg–1 g) those weighing more than 2–3 g are classified as giant parathyroid adenomas. Giant parathyroid adenomas are in fact rarely encountered among patients with primary hyperparathyroidism. They are believed to have distinct clinical and biochemical features related to specific genomic alterations. We chanced to manage a unique and possibly the first case of giant parathyroid adenoma (6 cm diameter and weighing 20 g) presenting with recurrent episodes of pancreatitis and discuss its surgical management with an added emphasis on the role of nuclear imaging in its preoperative localization. Our case demonstrates that clinicians should have a high index of suspicion of primary hyperparathyroidism in patients presenting with recurrent episodes of pancreatitis. Timely diagnosis, appropriate preoperative localization techniques, which would include a parathyroid scintigraphy and a focused surgical intervention are crucial to resolve complications and improve outcomes.

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Section: Discussionmentioning

confidence: 99%

A rare case of giant parathyroid adenoma presenting with recurrent episodes of pancreatitis

Raghunandan

Ramshankar

2016

Indian J Nucl Med

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“…10 Median sternotomy and thoracotomy are of great interest in cases of large inaccessible masses. 11 Our case showed that a trans-cervical excision of giant parathyroid adenoma is a viable approach for resection and should be considered prior to more aggressive approachs.…”

Section: Discussionmentioning

confidence: 77%

Giant Parathroid Adenoma With Thoracic Extension: A Case Report

Mbarek¹,

Belaid²,

Khamassi³

et al. 2018

Otolaryngol Open J

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A 31-year-old female patient was addressed to our consultation for management of hypercalcemia secondary to primary hyperparathyroidism. The physical examination results were normal. The technetium sestamibi (99m Tc MIBI) parathyroid scintigraphy showed a large fixation area next to the inferior pole of the left lobe of the thyroid. Cervical computed tomography (CT) scan showed a 6 cm tissue lesion in the inferior pole of the thyroid's left lobe. The patient was operated through a classical cervical incision, extracting successfully a 6 cm brown lesion. The histopathological study has confirmed the diagnosis of a giant parathyroid adenoma weighing 84 g.

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“…There is a documented procedure of excision of even giant parathyroid adenoma using minimally invasive transcervical approach after its radiological localisation pre-operatively resulting in full recovery. This case leads to the conclusion that this method is an advantageous alternative for neck exploration or sternotomy [44].…”

Section: Minimally Invasive Parathyroidectomy and Minimally Invasive Radio-guided Parathyroidectomymentioning

confidence: 75%

Primary hyperparathyroidism

Kowalski

Buła

Żądło

et al. 2020

Endokrynologia Polska

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Primary hyperparathyroidism is an endocrine disorder that results in overproduction of parathyroid hormone by overactivated parathyroid gland leading to a significant rise in blood serum calcium. It results in hypercalcaemia, which has a significant impact mainly on the kidneys and bones and results in a variety of signs and symptoms. Primary hyperparathyroidism should be treated because, if left without any therapy, it can lead even to death. Surgery is considered as the best and only successful therapy, with very low risk of recurrence and relatively low complication rate. The aim of this review is to present clinical basis, aetiology, diagnostic possibilities, and treatment opportunities.

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Day-case minimally invasive excision of a giant mediastinal parathyroid adenoma

Cited by 13 publications

References 3 publications

A rare case of giant parathyroid adenoma presenting with recurrent episodes of pancreatitis

A rare case of giant parathyroid adenoma presenting with recurrent episodes of pancreatitis

Giant Parathroid Adenoma With Thoracic Extension: A Case Report

Primary hyperparathyroidism

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