Date palm (Phoenix dactylifera L.) secondary metabolites: Bioactivity and pharmaceutical potential

Mohamed, Heba I.; El-Beltagi, Hossam S.; Jain, S. Mohan; Al–Khayri, Jameel M.

doi:10.1016/b978-0-12-824109-7.00018-2

Cited by 18 publications

(14 citation statements)

References 150 publications

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“…Among all of them, Ajwa palm contained greater quantities of TPC (113.70 mg/100 g), while Anbarah displayed the lowest concentration (81.41 mg/100 g) in contrast to the other flesh arrays. Some researchers [29] proposed that the date samples can supply an ample amount of phenolic and antioxidants, which confirm the significance of the date palm's rich energy and antioxidant properties to human health [29,30]. TPC results obtained in the current study were in agreement with previously published work [31,32].…”

Section: Chemical Composition Analysissupporting

confidence: 91%

“…The aforementioned results revealed that the Ajwa date palm has free radical scavenging capabilities, concurring with earlier performed studies for the diverse collection of date palm fruits [29]. Though the methanol extracts reported that superior antioxidant behaviour (p05), the differences were deemed insignificant Anwar and Przybylski [30].…”

Section: Antioxidant Activitiessupporting

confidence: 87%

“…Phenolics and flavonoids represent the largest phytochemical group among the other plant chemical constituents. Many researchers reported that it has health benefits for humans due to its antioxidant activities [29]. Accordingly, the date palm fruit can play a very good source of natural antioxidants and is considered a functional food ingredient [34][35][36]…”

Section: Chemical Composition Analysismentioning

confidence: 99%

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The chemical composition, total phenolic and antioxidant content of four date palm saudi cultivars

Assirey

2021

Journal of Taibah University for Science

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This work aims to study the antioxidant activities and chemical constituents of four Saudi date palm varieties (Ajwa, Kodari, Anbarah and Suqaey). Results showed variation in chemical composition and antioxidant activates. Carbohydrates (71.5-77.3 g/100 g dry matter) and moisture contents were the predominant competent in all flesh date palms (80.44-82.82%). Anbarah reported the highest protein and ash contents (3.50% and 2.32%, respectively) between the four varieties, while fat contents were low in the four types. Total phenols and antioxidant activities were higher in Ajwa compared to the other varieties. IC 50 of Ajwa, Kodari, Anbarah and Suqaey was 24.5, 25.55, 28.51 and 26.41 mg/ml, respectively. The antioxidant activities can be contributed to dates highly phenolic contents, which improve the antioxidant activities that could be used in food formulations.

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Section: Chemical Composition Analysissupporting

confidence: 91%

Section: Antioxidant Activitiessupporting

confidence: 87%

Section: Chemical Composition Analysismentioning

confidence: 99%

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The chemical composition, total phenolic and antioxidant content of four date palm saudi cultivars

Assirey

2021

Journal of Taibah University for Science

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“…Medicinal plants have historically been the preferred options for ameliorating pathological side-effects, as their own side effects are normally minor [ 16 ]. Phoenix dactylifera (date palm) is one of these plants that has been documented to treat liver-disease-related clinical symptoms in Arabian, Middle Eastern, and Northern African countries [ 17 ]. Middle Easterners have traditionally believed that eating dates on an empty stomach, especially in the morning, protects the liver from the action of toxic materials [ 18 ].…”

Section: Introductionmentioning

confidence: 99%

Methanolic Phoenix dactylifera L. Extract Ameliorates Cisplatin-Induced Hepatic Injury in Male Rats

El-Hak

Mahmoud²,

Ahmed

et al. 2022

Nutrients

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This study investigated the ameliorative potential of methanolic date flesh extract (MDFE) against cisplatin-induced hepatic injury. Twenty male rats (weighing 180–200 g) were allocated into four groups: control; date flesh (DF) group (oral 600 mg/kg MDFE for 21 days); Cis group (7.5 mg/kg i.p. at day 16); and date flesh/cisplatin (DF/Cis) group (oral 600 mg/kg MDFE for 21 days and 7.5 mg/kg i.p. at day 16). Hepatic biochemical parameters in sera, and inflammatory and oxidant/antioxidant hepatic biomarkers were estimated. Hepatic histological changes and the immunohistochemistry of cyclooxygenase-2 (COX-2), nuclear factor kappa B (NF-κB), and alpha smooth muscle actin (α-SMA) were assessed. Pretreatment with MDFE decreased Cis-triggered liver biochemical parameters, oxidative stress, inflammatory biomarkers, and histological damage. Moreover, MDFE treatment reduced Cis-induced hepatic NF-κB, COX-2, and α-SMA protein expression. MDFE exerted a hepatoprotective effect when used concomitantly with Cis. Its effect was mediated via its antioxidant and anti-inflammatory ingredients.

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“…Saudi Arabia is the second top world producer of dates and produced about 1.54 million tons of dates in 2019 from a 118 thousand hectare harvested area [ 1 ]. Dates are one of the most popular fruits in the world, and they are considered to be a good source of dietary fiber, glucose, fructose, potassium, magnesium, selenium, non-starch polysaccharides, and a wide variety of bioactive compounds, and consequently they possess antioxidant, antimicrobial, anticancer, anti-inflammatory, and anti-infertility activity [ 2 , 3 ]. In addition to direct consumption of fresh dates, they are processed into numerous products such as powder, syrup, juice, jam, relish, pickles, vinegar, and alcohol [ 4 ].…”

Section: Introductionmentioning

confidence: 99%

Physicochemical, Microbiological, and Sensorial Quality Attributes of a Fermented Milk Drink (Laban) Fortified with Date Syrup (Dibs) during Cold Storage

Alhamdan

Juhaimi

Hassan

et al. 2021

Foods

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This study investigated the nutritional, microbial, and sensory quality attributes of a fermented milk (laban) drink flavored with date syrup (dibs) during cold storage at 4 °C for 7 days. Date syrup was added to laban in specific proportions (2.5, 5, 7.5, 10, 12.5, and 15% date syrup/total weight of flavored laban) and an appropriate percentage (12.5%, 74 °Bx) was selected based on the sensory preference of panelists. The results indicate that flavoring laban with date syrup affected the physicochemical, nutritional, microbial, and sensory quality attributes of the product in different ways. Incorporation of date syrup in fresh laban drink significantly increased the pH, ash, protein, total solids, sugars, and magnesium (p < 0.05). However, acidity, fat, casein, lactose, calcium, total microbial count, and total yeast and molds count were decreased (p < 0.05). During storage, acidity, ash, and microbial load were concomitantly increased, while fat, casein, total solids, and sugars showed a concurrent reduction as the storage period progressed. The panelists preferred the freshly prepared flavored laban drink compared with the stored one, which is not surprising. After 7 days of storage, flavored laban drink was more acceptable than a non-flavored one. The findings of this research will help in fortifying dairy products with dates to create highly nutritious drinks without the addition of artificial additives, refined sweeteners, and preservatives, which at the same time would be accepted by consumers.

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Date palm (Phoenix dactylifera L.) secondary metabolites: Bioactivity and pharmaceutical potential

Cited by 18 publications

References 150 publications

The chemical composition, total phenolic and antioxidant content of four date palm saudi cultivars

The chemical composition, total phenolic and antioxidant content of four date palm saudi cultivars

Methanolic Phoenix dactylifera L. Extract Ameliorates Cisplatin-Induced Hepatic Injury in Male Rats

Physicochemical, Microbiological, and Sensorial Quality Attributes of a Fermented Milk Drink (Laban) Fortified with Date Syrup (Dibs) during Cold Storage

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