Dataset on the evaluation of antimicrobial activity and optical properties of green synthesized silver and its allied bimetallic nanoparticles

Akinsiku, Anuoluwa Abimbola; Dare, Enock O.; Ajani, Olayinka O.; Adekoya, J. A.; Adeyemi, Alaba Oladipupo; Ejilude, Oluwaseun; Oyeyemi, Kehinde D.

doi:10.1016/j.dib.2018.10.054

Cited by 6 publications

(2 citation statements)

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“…This toxicity can be modulated by changing the shape and size of the particles and modifying their surface, thanks to which we can obtain nanoparticles with the desired properties, and controlled toxicity [27,32]. An increasing number of studies confirm this potential [27,[33][34][35][36][37][38][39][40][41][42][43][44][45][46][47][48]. Currently, a significant number of nanosystems developed for medical use are composed of metallic nanoparticles with drug molecules attached to their surface, along with lipid particles or additional polymers.…”

Section: Introductionmentioning

confidence: 99%

Metallic Nanoparticles and Core-Shell Nanosystems in the Treatment, Diagnosis, and Prevention of Parasitic Diseases

Król,

Fortunka,

Majchrzak

et al. 2023

Pathogens

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The usage of nanotechnology in the fight against parasitic diseases is in the early stages of development, but it brings hopes that this new field will provide a solution to target the early stages of parasitosis, compensate for the lack of vaccines for most parasitic diseases, and also provide new treatment options for diseases in which parasites show increased resistance to current drugs. The huge physicochemical diversity of nanomaterials developed so far, mainly for antibacterial and anti-cancer therapies, requires additional studies to determine their antiparasitic potential. When designing metallic nanoparticles (MeNPs) and specific nanosystems, such as complexes of MeNPs, with the shell of attached drugs, several physicochemical properties need to be considered. The most important are: size, shape, surface charge, type of surfactants that control their dispersion, and shell molecules that should assure specific molecular interaction with targeted molecules of parasites’ cells. Therefore, it can be expected that the development of antiparasitic drugs using strategies provided by nanotechnology and the use of nanomaterials for diagnostic purposes will soon provide new and effective methods of antiparasitic therapy and effective diagnostic tools that will improve the prevention and reduce the morbidity and mortality caused by these diseases.

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Section: Introductionmentioning

confidence: 99%

Metallic Nanoparticles and Core-Shell Nanosystems in the Treatment, Diagnosis, and Prevention of Parasitic Diseases

Król,

Fortunka,

Majchrzak

et al. 2023

Pathogens

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“…The techniques revolve around chemical processes (sol-gel, colloidal, and spray pyrolysis), physical approach (sputtering, laser ablation, laser pyrolysis,) or biological approach (green synthesis, using plant stems, leaves, seeds, or microbes such as bacterial and yeast). These approaches are used under the scope of each research and the procedures that have been established [4][5][6][7][8].…”

Section: Introductionmentioning

confidence: 99%

Toxicity and Cytotoxicity Effects of Selected Nanoparticles: A Review

Odaudu

Akinsiku

2022

IOP Conf. Ser.: Earth Environ. Sci.

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The appreciable development in nanotechnology has drawn the attention of several researchers cutting across different fields. However, some nanoparticles have been identified to possess harmful effects on humans and the environment. Hence, putting these cause and effect patterns into context is highly required for future research and discussions about nanotechnology. This study reviewed existing literature on the toxicity and cytotoxicity effects of some nanoparticles to compare reaction patterns. Many kinds of research used different cell cultures, including cancer cell lines, human endothelial cells, hepatic cells, which were tested both in vitro and in vivo to check the mechanism of the possible toxicity effects. Adverse effects of nanoparticles identified involved damaged DNA leading to mutations and generation of reactive oxygen species (ROS). The prominent identified common toxicity responses in nanoparticle-cell interaction were lysosomes formation interference, necrosis and apoptosis, nanoparticles and protein interaction, and agglomerate formation in other body parts. Some reports showed that the causes of these responses might be due to the physicochemical properties of the interrogated particles, such as particle size, shape, surface functionalisation, surface charge. Furthermore, nanoparticles’ toxicity effects are both concentration-dependent and time-dependent, highly pronounced in chemical or physical-based synthetic routes. Cytotoxic effects of nanoparticles were mainly linked to their synthetic method, nature of the reducing agent, and culture media.

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