Database Analysis of Adults with Bipolar Disorder Consuming a Micronutrient Formula

Gately, Dermot; Kaplan, Bonnie

doi:10.4137/cmpsy.s2278

Cited by 18 publications

(30 citation statements)

References 22 publications

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“…The case presented here is the first to provide a cost analysis of this treatment, only the second to show benefit for symptoms of psychosis,2 and most importantly the first to provide empirical data documenting symptom response in the case of psychosis. As with a number of the other reports on the same formula,2 22 24 the child in this current report has been followed for a lengthy period of time, beyond the point at which expectancy effects would likely be influential.…”

Section: Introductionmentioning

confidence: 65%

Efficacy and cost of micronutrient treatment of childhood psychosis

et al. 2012

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Psychosis is difficult to treat effectively with conventional pharmaceuticals, many of which have adverse long-term health consequences. In contrast, there are promising reports from several research groups of micronutrient treatment (vitamins, minerals, amino acids and essential fatty acids) of mood, anxiety and psychosis symptoms using a complex formula that appears to be safe and tolerable. We review previous studies using this formula to treat mental symptoms, and present an 11-year-old boy with a 3-year history of mental illness whose parents chose to transition him from medication to micronutrients. Symptom severity was monitored in three clusters: anxiety, obsessive compulsive disorder and psychosis. Complete remission of psychosis occurred, and severity of anxiety and obsessional symptoms decreased significantly (p<0.001); the improvements are sustained at 4-year follow-up. A cost comparison revealed that micronutrient treatment was <1% of his inpatient mental healthcare. Additional research on broad-spectrum micronutrient treatment is warranted.

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Section: Introductionmentioning

confidence: 65%

Efficacy and cost of micronutrient treatment of childhood psychosis

et al. 2012

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“…As current pharmaceutical treatments have only partial benefit [1], other therapies such as nutritional interventions [2,3] continue to be investigated. Several lines of scientific evidence linking nutrition and mood exist.…”

Section: Introductionmentioning

confidence: 99%

Food intake and blood cholesterol levels of community-based adults with mood disorders

Davison

Kaplan

2012

BMC Psychiatry

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BackgroundA growing body of literature links nutrition to mood, especially in epidemiological surveys, but there is little information characterizing food intake in people with diagnosed mood disorders.MethodsFood intake obtained from 3-day food records was evaluated in 97 adults with mood disorders, whose diagnoses were confirmed in structured interviews. Information from a population nutrition survey, national guidelines for nutritional intakes (Eating Well with Canada's Food Guide) and North American dietary guidelines (Dietary Reference Intakes) was utilized to evaluate the quality of their food intake.ResultsCompared to the regional nutrition survey data and national guidelines, a greater proportion of study participants consumed fewer of the recommended servings of grains (p < 0.001) and vegetables and fruits (p < 0.05), and less than the lower boundary of the Adequate Macronutrient Distribution Range (AMDR) for α-linolenic acid (p < 0.001). The study sample also had greater intakes of high-fat whole grain products (p < 0.01), processed meats (p < 0.00001), and higher sugar, fat or salty foods (p < 0.00001). Of the 1746 total meals and snacks consumed, 39% were from sources outside the home, suggesting a lack of time devoted to meal preparation. Finally, a subsample of 48 participants agreed to have blood tests: 44% had mild hypercholesterolemia (> 5.2 and ≤ 6.2 mmol/L) and 21% had hypercholesterolemia (> 6.2 mmol/L).ConclusionsMuch research has proposed multiple ways in which healthier diets may exert protective effects on mental health. The results of this study suggest that adults with mood disorders could benefit from nutritional interventions to improve diet quality.

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“…For the 9 completers, improvement was significant on most outcome measures. A large database analysis of 682 adults with bipolar disorder taking EMP+, found that 53% experienced 50% improvement in psychiatric symptoms at 6 months (Gately & Kaplan, 2009). …”

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confidence: 98%