Data Supplement from Runx2 Is a Novel Regulator of Mammary Epithelial Cell Fate in Development and Breast Cancer

Abstract

<p>Supplementary Data File containing: Supplementary Figure 1 - Failed lobuloalveolar development in Runx2 knockout transplanted mammary glands is retained at the first day postpartum. Supplementary Figure 2 - Generation and validation of Runx2 floxed;MMTV-cre mice. Supplementary Figure 3 - Runx2 floxed;MMTV-cre mice exhibit slightly delayed ductal elongation during puberty. Supplementary Figure 4 - Runx2 regulates luminal progenitor populations in Runx2 knockout transplanted mammary glands. Supplementary Figure 5 - Forced Runx2 expression does not perturb prolactin induced Stat5 activation in HC11 cells.</p>