“…Concerning the German screening colonoscopy registry (to which the underlying data also contributed), a recent study indicated that the ADR is generally reliably documented, and data quality problems might therefore not have affected the current data to a large extent. 33 In addition to age and sex, further confounding factors could be taken into account in the case-mix adjustment. These include in principle all risk factors for colorectal neoplasia such as behavioral factors, personal and family history of colorectal neoplasia, inflammatory bowel disease, race, and ethnicty.…”