Data on the refractive index of freshly-excised human tissues in the visible and near-infrared spectral range

Matiatou, Maria; Giannios, Panagiotis; Koutsoumpos, Spyridon; Toutouzas, Konstantinos G.; Zografos, George; Moutzouris, K.

doi:10.1016/j.rinp.2021.103833

Cited by 14 publications

(5 citation statements)

References 15 publications

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“…Comparing our data with the human pancreas dispersion published in Ref. [42], which was calculated with only the first two terms in Eq. ( 6), our values within the visible-NIR range are higher, but we need to consider the difference in temperatures between studies.…”

Section: Resultssupporting

confidence: 53%

“…Fig. 6 presents such calculated dispersions for the spectral range of the experimental measurements (401-851 nm), along with some data for pancreas RI as collected from literature [41,42].…”

Section: Resultsmentioning

confidence: 99%

“…Regarding the evaluation of the RI of pancreas, only two studies have been published so far. One presents the RI of porcine pancreas for 632.8 nm at 20 ± 2 °C [41] and the other presents the calculated dispersion for human pancreas at 25 °C between 450 and 1550 nm [42].…”

Section: Introductionmentioning

confidence: 99%

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Estimation of Rabbit Pancreas Dispersion Between 400 and 1000 nm

Martins

Silva

Tuchin

et al. 2021

J-BPE

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Current biophotonics methods cover the entire optical spectrum from the deep ultraviolet to the terahertz. To optimize such methods for diagnostic and therapeutic applications, the need to obtain the wideband dispersion of tissues is high. The pancreas is a very important organ in the human body, since it produces insulin and its malfunction may induce diabetes. A reduced number of biophotonics publications regarding the pancreas is available, meaning that studies to determine its optical properties and their variation during optical clearing treatments are necessary. Considering this fact, we used the total internal reflection method to measure the refractive index of the rabbit pancreas for wavelengths between 400 and 850 nm. The experimental results allowed to calculate the pancreas dispersion with the Cauchy, Conrady and Cornu equations. It was observed that all those equations provided good data fitting in the spectral range of the measurements, but differences were observed outside these limits. Considering the wavelength of 633 nm, the mean value from the three dispersions was 1.3521, while the one published for porcine pancreas is 1.3517. The dispersion calculated with the Conrady equation does not present a fast decreasing behavior for shorter wavelengths as the ones calculated with the Cauchy and Cornu equations, but comparing these curves with a dispersion for a tissue-like material, all seem to have good agreement.

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Section: Resultssupporting

confidence: 53%

Section: Resultsmentioning

confidence: 99%

See 1 more Smart Citation

Estimation of Rabbit Pancreas Dispersion Between 400 and 1000 nm

Martins

Silva

Tuchin

et al. 2021

J-BPE

View full text Add to dashboard Cite

show abstract

“…Then, a pair of input values is needed to recover the real and imaginary component. This pair may comprise, for example, the critical angle of attenuated total reflection along with the reflectance at that point (θ c , R c ) [10,11], the pseudo-Brewster angle together with the reflectance at that point (θ B , R B ) [12], or the the pseudo-Brewster angle and the reflectance at normal incidence (θ B , R ⊥ ) [13].…”

Section: Introductionmentioning

confidence: 99%

Two Prism Critical Angle Refractometry with Attenuating Media

2022

Self Cite

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We present a concept that enables the determination of the complex refractive index of attenuating media from two critical angles, measured sequentially at two interfaces between a single sample and two different prisms. The proposed method is general in that it applies with s and p polarisation states, thus it is suited for the characterisation of isotropic as well as anisotropic media. Uncertainty analysis indicates that relative error in the determination of the real (imaginary) index can be less than 10−4 (in the order of 10%), respectively.

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“…Therefore, the innovation of this paper lies in highlighting the analysis of the cause of this phenomenon, and trying to create a sensor with excellent performance through a relatively simple structural design. The designed sensor can measure substances with RI of 1.35-1.41 in the NIR band, the RI of the cornea and lens of the human eye are 1.376-1.406 and 1.386-1.406 respectively, and the RI of biological tissues such as lung, liver and spleen varies in the range of 1.38-1.41 [15][16][17]. If the RI change of these biological samples can be accurately measured, it can provide an accurate judgment on the health status of biological tissues [18,19].…”

Section: Introductionmentioning

confidence: 99%

Characterization of incompletely coated D-shaped PCF-SPR refractive index sensors

Jiang,

Shen,

Feng

et al. 2023

Phys. Scr.

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To reduce the complexity of the sensor structure and improve the sensitivity of refractive index (RI) measurement, a D-shaped photonic crystal fiber (PCF) surface plasmon resonance (SPR) RI sensor with incomplete coating of gold-tantalum pentoxide (Au-Ta2O5) on the surface is proposed. When the coating width is 3.1μm, the sensor can detect RI samples ranging from 1.35 to 1.41 in the ultra-wide near-infrared (NIR) region of 1100-2100 nm wavelength. Its maximum wavelength sensitivity is 20,000 nm/RIU, maximum amplitude sensitivity is 2817.7 RIU-1, resolution is 5×10-6RIU, and figure of merit (FOM) is 333.3RIU-1. This sensor can be widely used in biological tissue detection. For this type of incomplete coated D-shaped sensor, the coating material and structural parameters not only affect the performance of the sensor, but also change the RI detection range, which has been ignored or not mentioned in previous literature on PCF-SPR sensors. Therefore, the reasons for the change of RI detection interval and negative optimization caused by structural parameters were analyzed, and two different sensors with different coating widths were finally obtained, which can achieve high sensitivity sensing in their respective detection intervals. The detailed research results expand the understanding of the SPR phenomenon in D-shaped PCF and provide theoretical guidance for adjusting and improving the detection performance of PCF-SPR sensors.

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Data on the refractive index of freshly-excised human tissues in the visible and near-infrared spectral range

Cited by 14 publications

References 15 publications

Estimation of Rabbit Pancreas Dispersion Between 400 and 1000 nm

Estimation of Rabbit Pancreas Dispersion Between 400 and 1000 nm

Two Prism Critical Angle Refractometry with Attenuating Media

Characterization of incompletely coated D-shaped PCF-SPR refractive index sensors

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