Abstract:<div>Abstract<p><b>Purpose:</b> To assess the role of Apollon in melanoma resistance to intrinsic and extrinsic pathways of apoptosis and to identify strategies to reduce its expression.</p><p><b>Experimental Design:</b> Apollon expression was assessed in melanoma cells <i>in vitro</i> and <i>in vivo</i>. Apollon modulation and melanoma apoptosis were evaluated by Western blot and/or flow cytometry in response to cytotoxic drugs, mitogen-a… Show more
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