Data from proteomic analysis of the skin of Chinese giant salamander (Andrias davidianus)

Abstract

The Chinese giant salamander (Andrias davidianus), renowned as a living fossil, is the largest and longest-lived amphibian species in the world. Its skin is rich in collagens, and has developed mucous gland which could secrete a large amount of mucus under the scraping and electric stimulation. The molting is the degraded skin stratum corneum. To establish the functional skin proteome of Chinese giant salamander, two-dimensional gel electrophoresis (2DE) and mass spectrometry (MS) were applied to detect the composition and relative abundance of the proteins in the skin, mucus and molting. The determination of the general proteome in the skin can potentially serve as a foundation for future studies characterizing the skin proteomes from diseased salamander to provide molecular and mechanistic insights into various disease states and potential therapeutic interventions. Data presented here are also related to the research article “Proteomic analysis of the skin of Chinese giant salamander (Andrias davidianus)” in the Journal of Proteomics [1].

Predicting Sex-Related Transcripts in the Chinese Giant Salamander (Andrias davidianus): A Transcriptomics Study, Selection Gender for Preservation, Breeding and Reintroduction

“…However, this is not always easy as some problems need to be solved due to the diversity of life. One such case is the giant salamander (Andrias davidianus), which belongs to the class Amphibia and is the largest of the three extant amphibians in the family Cryptobranchidae, also known as "living fossils" as their earliest found record was more than 350 million years ago [4,5]. Salamanders represent a transitional form between aquatic and terrestrial life and are considered a valuable model for the study of vertebrate evolution and biodiversity [6].…”