Abstract:<div>Abstract<p>The CCAAT/enhancer-binding protein <i>β</i> (C/EBPβ) plays a major role in the pathogenesis of anaplastic large cell lymphomas (ALCL) that express the nucleophosmin-anaplastic lymphoma kinase (NPM-ALK) tyrosine kinase (ALK<sup>+</sup>). Although ALK-mediated <i>C/EBPβ</i> transcriptional activation has been reported, <i>C/EBPβ</i> mRNA possesses U- and AU-rich domains in its 3′-untranslated region (3′-UTR) that might be privileged targ… Show more
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